University of Pennsylvania · 12 hours ago
Clinical Research Project Manager A/B/C
Philadelphia, PA
Full-time
Onsite
Mid, Senior Level
$62K/yr - $107K/yr
3+ years expThe University of Pennsylvania, a prestigious Ivy League institution, is seeking a Clinical Research Project Manager to oversee the operations of clinical research projects. The role involves managing day-to-day project activities, assisting with protocol development, and ensuring compliance with regulatory requirements while collaborating with internal teams and external partners.
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Responsibilities
Manages day-to-day operations of clinical research projects under guidance from senior staff
Assists with protocol development, project coordination at single or multicenter sites, and quality control of data
Supports grant applications, prepares reports and presentations, and contributes to dissemination of study findings
May supervise project staff and participate in study visits
Responsibilities include assisting with study start-up and maintenance activities, such as preparing and organizing study documents (protocols, informed consent forms, CRFs), supporting IRB submissions and amendments, tracking regulatory approvals, maintaining study binders, and assisting with development and upkeep of the study’s Manual of Procedures (MOP)
The Project Manager A supports preparation of meeting materials, reports, and study communications
This role coordinates study activities across internal teams and external collaborators, assists with scheduling meetings, tracking timelines and milestones, and supporting communication among investigators, study staff, and partners
The Project Manager A also assists with quality control efforts by tracking staff training and certifications, supporting monitoring activities, and ensuring adherence to established study procedures and regulatory requirements
The Project Manager A works closely with the PI, Clinical Research Coordinators, and grants management staff to support operational needs, including basic budget tracking and documentation
Serves as a point of contact for routine study-related inquiries and escalates complex issues as needed
Requires strong organizational skills, attention to detail, and effective communication
Works with moderate supervision and increasing independence over time
Serves as a primary liaison between the PI and study stakeholders, including Steering Committees, investigators, study staff, consultants, the IRB, and NIH
Works with the PI and grants management to oversee study budgets
Other duties as assigned
Responsibilities include leading study start-up activities, such as developing study documents (protocols, informed consent forms, CRFs), obtaining single IRB approval, preparing meeting materials and presentations, and designing, maintaining, and enforcing the study’s Manual of Procedures
The Project Manager B manages quality assurance and quality control activities, including staff training, data monitoring, certification tracking, and ensuring adherence to study and regulatory requirements
The Project Manager B collaborates with internal teams and external partners nationwide, overseeing study operations, timelines, and deliverables
In addition, the Project Manager B supports junior faculty research efforts, assists with grant development and submissions, and may lead subprojects or provide supervisory support as needed
Requires minimal supervision, strong communication skills, and demonstrated expertise in clinical research operations
Will serve as the primary liaison to internal teams, external collaborators, federal agencies, and funding sponsors
This role supervises and mentors project staff, while standardizing training, quality assurance, and operational practices across the program
Actively supports junior investigators in developing and executing research projects
Includes leading preparation and submission of large-scale grants (including multi-PI and center-level applications), managing budgets across active studies in collaboration with grants management, and overseeing dissemination efforts such as manuscripts and abstracts
This role requires a high degree of independence, advanced leadership skills, and extensive expertise in clinical research operations
Qualification
Required
Bachelor's Degree and 3-5 years of clinical research experience for Clinical Research Project Manager A
Experience assisting with study start-up and maintenance activities, including preparation of study documents (protocols, consent forms, CRFs, SOPs) and supporting IRB submissions and amendments for Clinical Research Project Manager A
Strong organizational, communication, and writing skills for Clinical Research Project Manager A
Ability to manage multiple tasks, meet deadlines, and work effectively both independently and as part of a team for Clinical Research Project Manager A
Master's Degree and 3-5 years of clinical research experience for Clinical Research Project Manager B
Experience in clinical research and managing epidemiologic studies for Clinical Research Project Manager B
Strong problem-solving, communication, and writing skills for Clinical Research Project Manager B
Ability to manage multiple priorities and tasks for Clinical Research Project Manager B
Knowledge of IRB and human research protection regulations for Clinical Research Project Manager B
Master's Degree and 5+ years of clinical research experience for Clinical Research Project Manager C
Extensive experience, including the independent management of complex, multi-site studies for Clinical Research Project Manager C
Strong track record of leading research operations, developing regulatory documents, and ensuring compliance for Clinical Research Project Manager C
Demonstrated expertise in coordinating multi-disciplinary teams for Clinical Research Project Manager C
Strong leadership, critical thinking, and communication skills for Clinical Research Project Manager C
Ability to prioritize and manage competing deadlines across multiple projects for Clinical Research Project Manager C
Familiarity with IRB processes and human subjects protection regulations for Clinical Research Project Manager C
Preferred
Familiarity with human subjects protection regulations for Clinical Research Project Manager A
Experience drafting protocols, consent forms, and related SOPs for Clinical Research Project Manager B
Benefits
Health, Life, and Flexible Spending Accounts: Penn offers comprehensive medical, prescription, behavioral health, dental, vision, and life insurance benefits to protect you and your family’s health and welfare. You can also use flexible spending accounts to pay for eligible health care and dependent care expenses with pre-tax dollars.
Tuition: Take advantage of Penn's exceptional tuition benefits. You, your spouse, and your dependent children can get tuition assistance here at Penn. Your dependent children are also eligible for tuition assistance at other institutions.
Retirement: Penn offers generous retirement plans to help you save for your future. Penn’s Basic, Matching, and Supplemental retirement plans allow you to save for retirement on a pre-tax or Roth basis. Choose from a wide variety of investment options through TIAA and Vanguard.
Time Away from Work: Penn provides you with a substantial amount of time away from work during the course of the year. This allows you to relax, take vacations, attend to personal affairs, recover from illness or injury, spend time with family—whatever your personal needs may be.
Long-Term Care Insurance: In partnership with Genworth Financial, Penn offers faculty and staff (and your eligible family members) long-term care insurance to help you cover some of the costs of long-term care services received at home, in the community or in a nursing facility. If you apply when you’re newly hired, you won’t have to provide proof of good health or be subject to underwriting requirements. Eligible family members must always provide proof of good health and are subject to underwriting.
Wellness and Work-life Resources: Penn is committed to supporting our faculty and staff as they balance the competing demands of work and personal life. That’s why we offer a wide variety of programs and resources to help you care for your health, your family, and your work-life balance.
Professional and Personal Development: Penn provides an array of resources to help you advance yourself personally and professionally.
University Resources: As a member of the Penn community, you have access to a wide range of University resources as well as cultural and recreational activities. Take advantage of the University’s libraries and athletic facilities, or visit our arboretum and art galleries. There’s always something going on at Penn, whether it’s a new exhibit at the Penn Museum, the latest music or theater presentation at the Annenberg Center, or the Penn Relays at Franklin Field to name just a few examples. As a member of the Penn community, you’re right in the middle of the excitement—and you and your family can enjoy many of these activities for free.
Discounts and Special Services: From arts and entertainment to transportation and mortgages, you'll find great deals for University faculty and staff. Not only do Penn arts and cultural centers and museums offer free and discounted admission and memberships to faculty and staff. You can also enjoy substantial savings on other goods and services such as new cars from Ford and General Motors, cellular phone service plans, movie tickets, and admission to theme parks.
Flexible Work Hours: Flexible work options offer creative approaches for completing work while promoting balance between work and personal commitments. These approaches involve use of non-traditional work hours, locations, and/or job structures.
Penn Home Ownership Services: Penn offers a forgivable loan for eligible employees interested in buying a home or currently residing in West Philadelphia, which can be used for closing costs or home improvements.
Adoption Assistance: Penn will reimburse eligible employees on qualified expenses in connection with the legal adoption of an eligible child, such as travel or court fees, for up to two adoptions in your household.
Company
University of Pennsylvania
The University of Pennsylvania is an American private Ivy League Research University that excels in producing future leaders.
10001+ employees
Funding
Current Stage
Late StageTotal Funding
$81.46MKey Investors
National Science FoundationUS Department of EnergyParent Project Muscular Dystrophy
2024-08-28Grant
2023-06-26Grant· $18M
2022-09-15Grant· $55M
Leadership Team
Mark Dingfield
Executive Vice President
Angela Duckworth
Rosa Lee and Egbert Chang Professor
Recent News
The Philadelphia Inquirer
2026-01-22
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