Matterworks · 18 hours ago
Data Manager
Somerville, MA
Full-time
Hybrid
Senior Level
6+ years expMatterworks is building AI tools to extract insights from biological data, seeking a Data Manager to establish their data management practices. The role involves owning the strategy and execution for transforming complex datasets into high-quality data assets, while collaborating with various teams to ensure data quality and usability.
Artificial Intelligence (AI)BiotechnologyMedicalPharmaceutical
Responsibilities
Data Strategy & E2E Ownership: Partner with scientific, ML, and product stakeholders to define a data roadmap: which datasets move the needle, which should be refreshed, and what “good enough” looks like for each use case. Establish clear success metrics for onboarding speed, dataset quality, and downstream usability (e.g., fewer training/data failures, higher match rates, better coverage, higher-confidence labels)
Dataset Sourcing, Discovery, and Intake: Proactively scout and integrate public and client datasets, plus relevant literature and reference materials, to keep our corpora current and comprehensive. Design a repeatable dataset intake workflow including provenance, source tracking, and refresh cadence
Data Curation, Quality and Governance: Define curation standards that make data consistent across sources and modalities, including compound identity management, biological/sample metadata standardization, and schema + conventions mappings. Build a scalable approach to integrating metabolomics now and expanding to additional omics without reinventing everything each time. Develop practical QC/QA frameworks that combine scientific judgment with repeatable checks
Cross-Functional Collaboration: Work closely with leadership in engineering, AI, product, and scientific discovery to align initiatives with company-wide goals. Use experience to keep initiatives moving smoothly. Translate ambiguous questions into crisp data requirements, priorities, and execution plans. Build trust across disciplines by being both scientifically rigorous and pragmatically execution oriented
Qualification
Required
6+ years of demonstrated experience owning scientific data work end-to-end (curation, standardization, QC, documentation, governance) in bioinformatics, cheminformatics, computational biology, scientific data engineering, or related roles
Ability to navigate complex chemical and biological datasets, reconcile identifiers/metadata across sources, and make data consistently usable for end users
Strong attention to detail with a keen ability to balance priorities and delivery incremental value while operating with minimal oversight
Comfortable building structure from scratch: you can define processes, set standards, and iterate toward scalable practices in an early-stage environment
Practical proficiency in Python and SQL for data investigation, transformation, QC, and automation
Familiarity with modern data workflows (structured + semi-structured data, pipelines, reproducibility, documentation)
Experience with chemical structure representations and normalization (e.g., SMILES/InChI, canonicalization, salt/tautomer handling, stereochemistry considerations)
Demonstrated ability to communicate and collaborate with product, machine learning, applied science and engineers while reducing complex business questions into valuable, reliable technical solutions
A passion for contributing to an early-stage startup where autonomy, eagerness to learn, and enthusiasm for solving novel scientific challenges prevail over rigid processes and egos
Benefits
Stock options
Health & dental
Vision
Long- and short-term disability
Life insurance
401k with company match
Flexible work & unlimited time away policy
Commuter benefits
Parking
Regular team meals and outings
Company support for continued education/coursework and conference participation
Company
Matterworks
Matterworks is a biotech startup that combines metabolomics with AI to simulate the metabolic environment.
51-200 employees
H1B Sponsorship
Matterworks has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (1)
Funding
Current Stage
Growth StageTotal Funding
$13.75MKey Investors
Germin8 Ventures
2025-06-03Series A
2023-08-14Seed· $7.5M
2023-01-01Convertible Note
Leadership Team
Jack (J.M.) Geremia, PhD
Chief Executive Officer
Recent News
globallegalchronicle.com
2025-07-05
2025-06-11
2025-06-11
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