NewLimit · 10 hours ago
Senior/Research Associate, Drug Product Development
South San Francisco
Full-time
Onsite
Mid, Senior Level
$75K/yr - $100K/yr
2+ years expNewLimit is a biotechnology company working to radically extend human healthspan. They are seeking a skilled and motivated Senior/Research Associate to join their Delivery Sciences team, focusing on the formulation, downstream processing, and characterization of lipid nanoparticles for nucleic acid delivery chemistries.
BiotechnologyClinical TrialsHealth Care
Responsibilities
Formulate, downstream process, and characterize LNPs for nucleic acid delivery across diverse model systems, including pre-clinical models
Partner with the Epigenetic Editing and Product teams (Immunology, Metabolism, Vascular) to meet LNP requirements for reprogramming interventions at both small and large scales
Develop and optimize LNP compositions, downstream processing and analytical methods to establish robust production protocols
Map future formulation needs, manage material procurement, and ensure the lab is equipped for upcoming programs
Interpret complex experimental data to drive decision-making within Delivery Science and Preclinical Development workstreams
Maintain rigorous and detailed records of experimental protocols and results in an Electronic Laboratory Notebook (ELN)
Qualification
Required
MS in Biomedical Engineering, Chemical Biology, Pharmaceutical Sciences, or a related discipline with 2+ years of industry experience or equivalent experience
Experience formulating LNPs with diverse lipid components for nucleic acid delivery
Experience with purification techniques, including dialysis, Tangential Flow Filtration (TFF), ultracentrifugation, and sterile filtration
Proficiency in LNP analysis using DLS, LC-UV, LC-CAD, CGE, fragment analyzers, Osmolality, MALS, ELISA, and fluorescence-based 96-well plate assays
Preferred
Experience contributing to drug product development at the preclinical or clinical stages
Background in liver biology or experience with LNP delivery to hepatocytes
Experience with bioconjugation, surface modification, or adding targeting moieties to LNPs to achieve cell type specificity
Experience with data visualization and statistical analysis (R, Python)
Benefits
Health, dental, and vision insurance
401(k) with company match
Paid parental leave
Industry-leading paid time off (PTO) — 20 days/year for all employees + holidays
Meals and snacks on-site
Company
NewLimit
NewLimit is a biotech company developing epigenetic therapies to extend human healthspan by reprogramming aging cells.
11-50 employees
H1B Sponsorship
NewLimit has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (2)
Funding
Current Stage
Growth StageTotal Funding
$247.25MKey Investors
Kleiner Perkins
2025-10-20Convertible Note· $45M
2025-05-06Series B· $130M
2023-05-16Series A· $72.25M
Leadership Team
Blake Byers
Co-Founder
Recent News
Longevity.Technology - Latest News, Opinions, Analysis and Research
2025-11-28
2025-11-17
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