Karius · 9 hours ago
Manager, Commercial Operations
United States
Full-time
Remote
Mid, Senior Level
$124K/yr - $186K/yr
6+ years expKarius is a life science company focused on advancing diagnostic science and technology for infectious diseases through microbial insights. The Manager of Commercial Operations will enhance Karius' commercial organization by optimizing processes, systems, and data infrastructure while partnering with various teams to drive performance and execution throughout the commercial lifecycle.
BiotechnologyGeneticsHealth CareInformation TechnologyLife SciencePrecision Medicine
Responsibilities
Lead improvements to commercial processes and workflows across the go-to-market lifecycle (lead-to-opportunity-to-order-to-cash), ensuring clarity, consistency, and adoption
Partner with stakeholders to identify process gaps, define requirements, and deliver scalable solutions across CRM (Salesforce), marketing systems (HubSpot), and downstream integrations
Maintain governance of commercial master data (accounts, contacts, territories, referring institutions, attribution rules, etc.), including documentation and quality controls
Build and maintain process documentation, SOPs, and training materials to ensure consistency and enablement
Own the Commercial Ops intake and ticketing process (e.g., JIRA/other), including required fields, prioritization, assignment, and closure standards
Maintain clear SLAs (e.g., 48-hour response/turnaround where applicable), proactively communicating risks, dependencies, and timeline changes before deadlines slip
Maintain a transparent tracker/backlog for all workstreams and requests, including priority, owner, due date, dependencies, and next steps
Partner with the Commercial Operations leader to drive pipeline discipline, forecasting accuracy, and consistent inspection routines (weekly/monthly/quarterly)
Support annual comp, quota/goal, and territory planning (analysis, scenarios, and execution) in partnership with the Commercial Operations leader
Own pipeline and funnel reporting, including stage definitions, conversion metrics, velocity, and leading indicators
Ensure consistent reporting definitions and governance, and maintain stakeholder trust in metrics and reporting
Develop and maintain dashboards and reporting that provide clear visibility into performance, pipeline, activity, and operational health
Design and develop complex queries, comprehensive reports, and analyses to facilitate fact-based business decisions
Perform business intelligence and analytics reporting to support commercial and field team initiatives
Translate analysis into decision support: succinct insights, implications (“so what”), recommendations, and execution next steps with owners and timelines
Create stakeholder-ready outputs (leadership updates, summaries, dashboards, and analyses) with minimal rework required
Establish reporting definitions, QA checks, and governance to ensure accuracy and stakeholder trust
Support deal execution and deal desk processes as needed (quoting, approvals, routing, contracting coordination), ensuring accuracy and speed
Partner with Finance/Ops/Legal as appropriate to ensure contract and deal workflows are executed correctly and on time
Partner with Marketing and Sales to define and govern lead flow, handoffs, SLAs, attribution, and event ROI reporting by translating performance into clear recommendations for future investment
Drive enablement for commercial process changes by tailoring training and communications for a field audience to ensure adoption
Qualification
Required
Bachelor's degree required; graduate degree preferred
A minimum of 6-8 years of experience; Master's degree with 4-6+ years of experience in Commercial Operations, Sales Operations, Revenue Operations, Business Operations, or related function in a high-growth environment
Extensive CRM and commercial systems experience (Salesforce and BI tools required; HubSpot, JIRA/Asana preferred)
Proven ability to build scalable processes, governance, and operating rhythms across cross-functional stakeholders
Strong analytical skills with the ability to translate data into actionable business recommendations
Excellent project management and execution skills, including prioritization, tracking, dependency management, and on-time delivery
Proven ability to communicate with clarity and concision across levels, including senior leadership and field teams
High attention to detail with experience implementing QA controls and maintaining data integrity
Experience supporting healthcare, diagnostics, lab operations, or regulated environments
Company
Karius
Karius delivers genomic insights into infectious diseases, helping clinicians make critical, life-saving treatment decisions.
51-200 employees
H1B Sponsorship
Karius has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2024 (1)
2021 (4)
Funding
Current Stage
Growth StageTotal Funding
$354MKey Investors
SoftBank Vision FundOxford Finance LLCDCVC
2024-05-02Series C· $100M
2020-02-24Series B· $165M
2018-11-30Debt Financing· $25M
Leadership Team
Alexander Ford
Chief Executive Officer
Tim Blauwkamp
Chief Scientific Officer, Co-founder
Recent News
General Catalyst
2026-01-06
2025-05-04
Company data provided by crunchbase