Denali Therapeutics · 6 hours ago
Associate Scientist, Cell Line Development
South San Francisco
Full-time
Onsite
Entry, Mid Level
$122K/yr - $146K/yr
2+ years expDenali Therapeutics is a biotechnology company focused on developing therapies for neurodegenerative diseases. They are seeking a highly motivated scientist to join their Bioprocess Development team, focusing on generating commercially viable cell lines for therapeutic molecules.
BiotechnologyGeneticsHealth DiagnosticsTherapeutics
Responsibilities
Support the development of Denali’s mammalian biotherapeutic production platform to generate commercially viable cell lines
Execute cell line development activities including transfection, selection, single cell sorting, clone imaging, clone selection, and clone banking for pipeline projects
Design, execute, and interpret cell line development experiments in collaboration with other scientists in the group, including the use of JMP statistical software for DOE experiments and generating figures
Write technical and summary reports including cell line development reports which serve as source documents for regulatory filings, effectively communicate findings with cross-functional teams, and participate in scientific discussions with scientific teams
Maintain accurate and detailed laboratory notebook and relevant documentation
Cross-functionally support cell culture process development through bioreactor production runs and DOE-based screening experiments as necessary
Evaluate, optimize, and implement characterization assays such qPCR, Western blots, and flow cytometry
Qualification
Required
BA/BS or MS degree in Molecular Biology/Biochemistry/Cell Biology or related field
Technical proficiency in mammalian cell culture and upstream process development preferably in an industrial laboratory
2+ years of experience working in a laboratory environment
Demonstrated ability to organize, analyze, and interpret experimental data, specifically in JMP and Excel
Ability to work effectively and collaboratively with other scientists in cross-functional project teams
Excellent oral presentation and written communication skills
Preferred
Experience in CHO cell line development for biologics
Proficiency with protein characterization techniques such as Octet, SDS-PAGE, Caliper, and HPLC
Benefits
401k
Healthcare coverage
ESPP
A broad range of other benefits
Company
Denali Therapeutics
Denali Therapeutics is dedicated to defeating neurodegenerative diseases to deliver safe and effective medicines to patients and families.
501-1000 employees
H1B Sponsorship
Denali Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (11)
2024 (14)
2023 (7)
2022 (6)
2021 (5)
2020 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.32BKey Investors
Royalty PharmaBaillie Gifford
2025-12-04Post Ipo Debt· $200M
2024-02-27Post Ipo Equity· $500M
2022-10-19Post Ipo Equity· $275M
Leadership Team
Ryan Watts
CEO
Peter Chin
Sr. Vice President & Head of Late-Stage Clinical Development and Medical Affairs
Recent News
2026-01-11
Longevity.Technology
2026-01-03
Company data provided by crunchbase