GSK · 2 weeks ago
Principal Scientist, Neurology
USA - Pennsylvania - Upper Providence
Full-time
Onsite
Senior Level, Lead/Staff
3+ years expGSK is a global biopharma company aiming to impact the health of 2.5 billion people by the end of the decade. They are seeking a Principal Scientist in Neurology to support research in neurodegenerative diseases, working within a dynamic team to harness the power of the immune system for therapeutic advancements.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Support discovery projects by establishing and performing in vitro iPSC derived CNS cells/ ex vivo cellular assays using high-content imaging, molecular and biochemical readouts
Develop novel assays with high translational value to interrogate target or disease biology
Develop target and biomarker hypothesis based on Omics data
Optimize and perform in vitro assays to support lead optimization of molecules
Work collaboratively with matrix partners to drive towards project milestone
Periodically update work status to project teams and matrix partners
Manage time efficiently and be productive when there are competing priorities
Be compliant with GSK policies and SOPs including recording electronic laboratory notebooks, maintaining safety while working in the lab
Qualification
Required
PhD with 3+ years of postdoctoral experience in Neuroscience/Neurodegeneration
Experience with aseptic cell culture techniques especially for long term culture without antibiotics
Experience with standard laboratory techniques such as immunofluorescence assay, plate- or bead-based immunoassay, molecular biology techniques such as western, qPCR, transfection, or high content imaging etc
Experience in developing assays based on target mechanisms/ biology in the context of neurodegeneration
Experience with AI/ML tools for discovery research
Preferred
3+ years' industry experience working in matrix environment
Working experience with iPSC derived neurons/ astrocytes/ microglia for disease modeling
Familiarity with different screening platforms used in drug discovery
Basic hands on bioinformatic skills
Effective communication skills and being proactive at work
Company
GSK
We are uniting science, technology and talent to get ahead of disease together. Our community guidelines: https://gsk.to/socialmedia
10001+ employees
H1B Sponsorship
GSK has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (45)
2024 (56)
2023 (54)
2022 (53)
2021 (54)
2020 (72)
Funding
Current Stage
Public CompanyTotal Funding
$25.51MKey Investors
CARB-X
2021-03-02Grant· $18M
2020-09-23Grant· $7.51M
1978-01-13IPO
Leadership Team
Julie Brown
CFO
Mike Elmore
SVP & Chief Information Security Officer, GSK
Recent News
2026-01-16
2026-01-13
South China Morning Post
2026-01-08
Company data provided by crunchbase