Vertex · 2 hours ago
Director Global HEOR, Povetacicept
Boston, MA
Full-time
Hybrid
Director/Executive
10+ years expVertex is a global biotechnology company that invests in scientific innovation, and they are seeking a Director for their Global Health Economics & Outcomes Research (HEOR) group. The role involves leading HEOR strategies and executing evidence generation to optimize the value proposition of Vertex’s povetacicept assets throughout their development lifecycle.
Computer Software
Responsibilities
Serves as the HEOR povetacicept Lead focusing on pipeline indications: pMN and/or gMG
Develops the HEOR strategy for povetacicept from early development through product lifecycle
Serves as HEOR lead to cross-functional and cross-regional teams to align strategic plans to stakeholder needs and represent the voice of HEOR
Execute complex HEOR evidence generation including, cost-effective analysis and budget impact models, prospective and retrospective observational studies, ITCs, meta-analyses and systematic reviews, patient reported outcomes measure development and validation and other research as needed to support the asset value
Gathers and synthesizes insights from Payers, KOLs and HEOR experts; stays current with scientific and policy trends and best practices and applies strategic and content expertise to strategy planning
Supports the integration of HEOR evidence in health technology appraisal submissions for relevant assets
Collaborates with the medical communications teams on publication strategy and ensure that dissemination of HEOR evidence is timely and has maximum impact
Partners and works closely with Global Pricing and Market Access to support production of GVD and Value Narrative
Collaborates closely with global brand marketing, clinical, and other functional teams to support and enhance access to marketed products across various regions and serves as HEOR lead to cross-functional teams
Oversee the design and execution of HEOR studies and apply best practices for HEOR analyses, modeling and dissemination; ensures the highest quality standards for research and dissemination
Qualification
Required
Advanced degree (PhD, MD, Master's degree, MPH, or PharmD) in a relevant discipline
Typically requires 10 years of experience in health economics and outcomes research, or directly-related field and industry, or the equivalent combination of education and experience
Provides technical expertise in HEOR and able to formulate and lead creative research projects and ensure conduct is technically and scientifically rigorous and reflects best HEOR practices
Strong track record of publications in peer-reviewed journals demonstrating experience in evidence synthesis, patient reported outcomes, observational research, and health economic modeling
Demonstrate capabilities to develop global strategic HEOR plans and execute studies with comprehensive understanding of clinical development strategies and trial designs
Ability to apply knowledge of US healthcare system, global health technology appraisal requirements, and clinical development plans, to identify evidence gaps and formulate evidence generation strategies
Strong verbal and written communications skills, including presentation skills to communicate difficult concepts and persuade others; comfortable communicating complex concepts and adapting presentation style to a variety of audiences
Broad and comprehensive understanding of the legal and regulatory environment of the pharmaceutical industry, demonstrated integrity on work-related compliance considerations and solid ethics
Preferred
Market Access experience, including direct experience in making submissions to relevant payers and interacting with them is strongly desired (US and EX-US)
Benefits
Medical, dental and vision benefits
Generous paid time off (including a week-long company shutdown in the Summer and the Winter)
Educational assistance programs including student loan repayment
A generous commuting subsidy
Matching charitable donations
401(k)
Company
Vertex
Vendor intelligence that combs through your supplier, manufacturer, logistics data to detect where you're leaving money on the table.
2-10 employees
H1B Sponsorship
Vertex has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (27)
2024 (18)
2023 (7)
2022 (13)
2021 (5)
2020 (7)
Funding
Current Stage
Early StageCompany data provided by crunchbase