CAMRIS · 1 day ago
Sr. Scientist
US-MD-Gaithersburg
Full-time
Onsite
Senior Level, Lead/Staff
8+ years expCAMRIS is a dynamic clinical research and international development firm that achieves innovative solutions to health and development challenges through high-quality, cost-effective programs and research management services. They are seeking a Sr. Scientist to support the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases (NIAID) in conducting groundbreaking research in vaccine and antibody development.
BiotechnologyInformation Technology
Responsibilities
Conduct upstream process development and tech transfer of production processes toward clinical manufacturing of VRC vaccine and antibody clinical candidates within the Cell Culture Development group at the VPP
Provide subject matter expertise to lead scientists and/or associates to develop upstream process methods that meet the productivity and product quality characteristics to achieve successful production of clinical material. Including:
Designing optimization studies (e.g., DOE with JMP)
Use of high-throughput automated AMBR15 and AMBR250 bioreactors
Use of fed-batch bench scale bioreactors and scalable Single-Use-Bioreactors SUBs at 50 L (supporting 250 L, 1000 L, and 2000 L manufacturing vessels)
Develop pDNA production platform using microbial cell cultures in both shake flask and controller-programmed stirred-tank bioreactor formats
Collaborate with Project Managers to ensure upstream development milestones are appropriately set and met on time
Serve as a subject matter expert (SME) in guiding cell culture strategies (media/feed evaluation, control parameter tuning, etc.) for new vaccine or therapeutic mAb candidates (both mammalian and microbial cultures)
Responsible for process evaluation/finalization and oversight of process-locked scale up runs to generate material for toxicology studies. Including, editing/approving/execution of process protocols and production. reports
Coordinate closely with Manufacturing teams to ensure timely and scale appropriate Technology Transfer is achieved, by pursuing the following:
Write/edit/review tech transfer documents (Process Descriptions/Process Flow Diagrams)
Serve as Person in Plant or assign designee for initial VCMP production runs
Serve as SME in VCMP upstream troubleshooting and facility fit evaluations
Serve as the VRC upstream SME in external collaborations
Generate necessary regulatory docs to enable IND submissions, FDA response, etc
Optimize lab operational space, in collaboration with Process Team Operations Manager and VPP Scientific Operations group, to implement and sustain an optimal productive lab environment (e.g., 5S organizational efforts, KANBAN, or other structural initiatives)
Encourage and drive innovation to meet new upstream challenges and seeks to publicly distribute novel technologies through presentations at national conferences and/or publication in peer-reviewed journals
Performs other duties as assigned
Qualification
Required
PhD in Bioengineering, Chemical Engineering, Biochemistry, or related discipline
Minimum of eight (8) years of experience microbiology and/or cell culture research and development
Demonstrated knowledge of maintaining accurate and detailed records
Must be a team player who can effectively work with members from cross-functional departments
Strong oral and written communication skills
Familiarity with computer software including word processing and data evaluation
Ability to lift or carry less than 25 pounds, push or pull less than 25 pounds, push or pull 25 – 45 pounds, reach above shoulder level, and use both hands
Will be required to stand or walk more than 25 of 30 min., bend repeatedly, and climb
Must have depth perception, correctable near vision, ability to distinguish basic colors, and perform repetitive activities
Ability to work alone and closely with others, work on ladders or scaffolding, work around machinery with moving parts, work with hands in water, and with solvents
Will be required to be in contact with laser in instrument
Will work with corrosive substances, inorganic dust and powders, heavy metals, plastics, solvents, and sensitizing agents
Must be able to wear personal protective equipment (PPE), including gloves, face shields/goggles, safety glasses, safety shoes, lab coat, clean room uniform, and disposable dust/surgical mask
Benefits
Medical, dental, and vision insurance for individuals and families
FSAs
HSA
Life and AD&D insurance
Short- and long-term disability
Legal services
Voluntary hospital indemnity
Critical illness and accident insurances
EAP
Pet insurance
401(k) with employer match and Roth option
Tuition and professional reimbursement
Public transportation support in the DMV area
A referral bonus program
Vacation with tenure-based increases
PTO
11 paid holidays
Paid bonding leave
Paid supplemental short-term disability
Company
CAMRIS
CAMRIS is a military medicine, clinical and life sciences, and research and development firm with experience working in more than 110 countries.
51-200 employees
H1B Sponsorship
CAMRIS has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
2024 (2)
2023 (2)
2021 (2)
Funding
Current Stage
Growth StageTotal Funding
unknown2020-10-05Acquired
Company data provided by crunchbase