Vaxcyte · 13 hours ago
Associate Director, Real-World Evidence & Epidemiology
San Carlos, California, United States
Full-time
Hybrid
Senior Level, Lead/Staff, Director/Executive
$199K/yr - $232K/yr
6+ years expVaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from bacterial diseases. They are seeking an Associate Director, Real-World Evidence & Epidemiology to execute and expand their epidemiology and real-world evidence capabilities across the vaccine lifecycle, combining operational leadership with scientific execution.
BiopharmaBiotechnologyHealth Care
Responsibilities
Lead end-to-end execution of epidemiology and RWE studies, including retrospective database studies, prospective observational studies, and hybrid designs, supporting both pediatric and adult vaccine programs
Manage study start-up activities including contracting, budgets, timelines, and SOWs with CROs, academic partners, and data vendors
Oversee IRB and ethics submissions and ensure compliance with regulatory, privacy, and data governance requirements
Partner closely with Legal, Procurement, and Compliance to ensure timely and compliant study execution
Contribute to study design, protocol development, and statistical analysis plans in collaboration with internal scientific partners
Conduct or oversee hands-on analyses using real-world data sources (e.g., claims, EHR, surveillance systems), including data quality checks and exploratory analyses
Support and/or lead retrospective analyses, prospective cohort studies, systematic literature reviews, and meta-analyses relevant to pneumococcal disease and vaccine effectiveness across age groups
Work with large datasets and analytic tools (e.g., SAS, R, STATA) to support internal analyses and to critically review and interpret CRO-generated outputs
Lead or contribute to abstracts, manuscripts, white papers, and conference presentations
Translate complex scientific and epidemiologic findings into clear, actionable insights for diverse internal audiences, including commercial partners, medical science liaisons, HEOR, legal, and regulatory teams
Support consistent, high-quality interpretation of evidence across Vaxcyte’s epidemiology and RWE portfolio
Help establish best practices, templates, and SOPs for epidemiology and RWE study conduct
Build strong working relationships with academic collaborators, public health partners, and external vendors
Gradually assume greater scientific leadership and ownership of the epidemiology portfolio as the function grows
Qualification
Required
Master's degree in Epidemiology, Public Health, Biostatistics, or a closely related field, with 8 years of experience in epidemiology, real-world evidence, or observational research within biotech, pharma, academia, public health, or a CRO required
Demonstrated experience planning and executing observational studies, including retrospective and/or prospective designs
Experience working with real-world data and analytic tools (e.g., SAS, R, STATA), including data management, analysis, or close oversight of analyses
Ability to clearly present complex scientific and epidemiologic data to non-technical audiences, both verbally and in writing
Strong scientific judgment, organizational skills, and ability to independently manage multiple workstreams in a fast-paced environment
Preferred
PhD or DrPH in Epidemiology or a related discipline with 6 years experience preferred
Prior experience at the CDC, including Epidemic Intelligence Service (EIS) or similar applied epidemiology training programs
Experience conducting or contributing to systematic literature reviews and meta-analyses
Experience working with large healthcare databases (e.g., claims, EHR, surveillance systems)
Prior experience in vaccine research, infectious disease epidemiology, or respiratory disease
Track record of contributing to peer-reviewed publications and major scientific meetings
Prior experience with health economic modeling
Interest in growing into a scientific leadership role within industry
Benefits
Comprehensive benefits
Equity component
Company
Vaxcyte
Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.
201-500 employees
Funding
Current Stage
Public CompanyTotal Funding
$3.85BKey Investors
CARB-XTPG GrowthAbingworth
2024-09-04Post Ipo Equity· $1.5B
2024-01-30Post Ipo Equity· $862.5M
2023-04-19Post Ipo Equity· $500M
Leadership Team
Andrew Guggenhime
President & Chief Financial Officer
Jeff Fairman
Founder and Vice President, Research
Recent News
2025-12-09
Company data provided by crunchbase