Pfizer · 19 hours ago
Global Development Product Lead (Executive Director)
La Jolla, CA
Full-time
Hybrid
Director/Executive
$296K/yr - $479K/yr
10+ years expPfizer is a global leader in healthcare, and they are seeking a Global Development Product Lead to lead multiple cross-functional oncology product teams through early clinical development stages. The role involves developing strategic plans for early development assets, ensuring timely execution of product milestones, and collaborating with various stakeholders to drive innovation in oncology research.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
No H1B
U.S. Citizen Only
Responsibilities
Leads multiple (~2-4) cross functional oncology product teams from pre-clinical candidate nomination (CAN) through Phase 1-2 clinical development and proof of concept (POC) stages, at which point molecule may be handed to the late-stage Oncology Development team for post-POC (typically phase 3) development
In close collaboration with functional experts on the product teams, drives the effective integration of an end-to-end cross functional molecule strategy and risk mitigation plan and ensures delivery of data-driven milestones through successful risk identification and mitigation
Support clinical trials and the development strategy for early development assets and lead development programs across multiple functions within Pfizer Oncology, as well as represent the program with the external clinical community
Develop clinical development plan from first in human clinical trial to proof-of-concept, including assessment of appropriate combinations, as well as evaluation of potential predictive and pharmacodynamics biomarker plans
To ensure the cross-functional components of the product plans including clinical expertise are provided to project teams, including medical monitoring of clinical trials
Substantial support of CDP development and diligence for external innovation activities
Lead key enterprise level cross-functional workstreams to accelerate R&D decision making
Lead, develop and execute strategic development for early development assets. Lead cross-functional teams in collaboration with line function experts on the Global Product Teams (GPTs) to develop and drive an integrated product plan that addresses near-term technical uncertainties and ensures alignment with future pivotal development and commercialization success
Ensure timely execution and delivery of product milestones within budget
Communicate with executive management and governance committees to address program needs and provide recommendations. Ensure clear and effective product presentations and communications
Collaborate with partners on co-development programs to deliver a shared global product strategy, when applicable
Lead the team to set objectives, prioritize tasks, and ensure adherence to the plan and strategy
Manage risk by proactively identifying and resolving issues and developing contingency plans
Oversee early development assets’ development broadly within a specific indication or group of indications. Typically, work on at least two to four clinical programs and support the development and provide consultation regarding multiple research projects
Work across the organization and on multifunctional teams responsible for the development of early development assets (including Product Team, Global Development Team, and Study team)
Oversee the development and management of clinical protocols and amendments, investigator brochures, clinical study reports, statistical analysis plan, and regulatory documents
Provide leadership to early stage clinical scientists on the clinical study team for Early Development Assets, working in a matrix team environment with other clinicians, statisticians, clinical pharmacologists, translational biologists and regulatory specialists. Meet regularly with Pfizer Oncology group leaders/surrogates across functions to increase mutual awareness and influence of emerging program targets, priorities and status
Implementation of PK-guided dose escalation, early combination strategies and emerging innovations on all Oncology R&D first-in-human clinical trials with input from Pfizer Oncology’s Oncology Research Unit, Regulatory Strategy, Clinical Pharmacology and Precision Medicine, Clinical Development and Operations, Pharm Sci and Product Teams
Oversee the evaluation of safety, pharmacology, and efficacy data from ongoing and completed studies for early development assets
Oversee manuscripts, abstracts and presentations for scientific meetings and advisory boards
Conduct literature reviews and prepare summaries to support clinical development programs
Medical resource for design and interpretation of clinical and preclinical programs to support existing and new development candidates
Coordinate regular (at least quarterly and as needed) interactions with preferred clinical trials network and KOL advisory board to objectively consider and implement feedback
Drive innovations in early clinical development, and the application of translational oncology and precision medicine approaches
Collaborates with cross-functional leaders and teams to translate early preclinical discovery research into therapeutic candidates
Coordinates with business development to establish strategic external collaborations and foster new research projects and programs
Contribute to broader organizational excellence as a member of the OESD department. Create a positive team environment that fosters trust, encourages the sharing of disconfirming information, and promotes clear and transparent communication to align the team around the overall goal and vision for the product
Qualification
Required
MD or MD-PhD with 10+ years of industry experience in oncology drug development is preferred, track record in oncology clinical research including early phase drug development
Clinical oncology experience: Board certification in oncology preferred
Significant industry leadership experience in clinical, translational or basic research in biomedical sciences or one of the disciplines related to drug development
Understanding of related disciplines (e.g., biostatistics, regulatory, pre-clinical pharmacology, pharmaceutical sciences)
Demonstrated scientific productivity (publications, abstracts, etc.)
Proven scientific writing skills and good communication skills
Proven leadership skills with ability to defend the clinical plan at governance meetings is essential
Capacity to adapt to a fast-paced and changing environment
Demonstrated history of effective leadership; including cross functional and matrixed teams, managing direct reports when applicable, and experience in seeking and maintaining alignment with cross-functional leaders
Demonstrates a passion for helping patients with cancer and for the science of oncology
A proactive and strategic thinker, with strong data-driven decision-making skills
Ability to focus and motivate a team in a matrix organization with multiple stakeholders
Strong verbal, written, and presentation communication skills
Effective mentoring experience and skills
Highly collaborative with outstanding relationship building skills with internal company leadership, external development partners and investigators/medical professionals
Has a strong leadership presence and the ability to work effectively with other leaders. Ability to influence up and across the organization from an enterprise level
Is a team player, works well in a team environment both as a leader and a key contributor
Has a global perspective and mindset, with the ability to work effectively with colleagues from myriad cultures, backgrounds, and geographies
Benefits
Participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary
Eligibility to participate in our share based long term incentive program
401(k) plan with Pfizer Matching Contributions
Additional Pfizer Retirement Savings Contribution
Paid vacation
Holiday and personal days
Paid caregiver/parental and medical leave
Health benefits to include medical, prescription drug, dental and vision coverage
Company
Pfizer
Pfizer is a biopharmaceutical company that discovers, develops, and delivers medicines and vaccines.
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$38BKey Investors
Starboard Value
2025-11-21Post Ipo Debt· $6B
2024-10-07Post Ipo Equity· $1B
2023-05-16Post Ipo Debt· $31B
Leadership Team
Albert Bourla
Chief Executive Officer
Ian Read
Chief Executive Officer
Recent News
2026-01-24
Labiotech UG
2026-01-24
Company data provided by crunchbase