Merge Labs · 18 hours ago
Scientist - Gene Delivery
San Francisco, CA
Full-time
Onsite
Mid, Senior Level
$165K/yr - $215K/yrMerge Labs is a frontier research lab focused on bridging biological and artificial intelligence to enhance human capabilities. The Scientist in Gene Delivery will engineer and validate gene delivery approaches for novel molecular biosensors and actuators, collaborating with a multidisciplinary team to optimize and produce gene delivery vectors.
BiotechnologyHuman ResourcesSoftware
Responsibilities
Develop preclinical gene delivery approaches using established vectors such as AAVs
Optimize and validate the delivery of biosensor and actuator constructs in vivo
Establish the production of vectors in-house and/or through external partners
Collaborate with molecular engineering and neurobiology colleagues on payload design and expression requirements
Originate and test novel gene delivery vectors and strategies, including viral and non-viral, and developed in-house and partnered
Recruit and mentor research associate(s) as needed to expand efforts
Qualification
Required
a Ph.D. or equivalent experience leading research projects end-to-end in bioengineering, neuroscience, cell biology, molecular biology or a related field
Engineered AAVs and/or worked with them extensively to deliver genes to the brain in preclinical models
Demonstrated expertise in developing or optimizing gene delivery modalities
Developed and used methods to evaluate gene delivery and expression in brain tissues
Optimized titers, delivery routes, timing and other parameters to achieve specific expression goals
Worked on a delivery-related problem that is unusual or complex and loved it
Fun working on multidisciplinary teams, collaborating and communicating with experts across disciplines
The desire to be part of a fast-paced team working on frontier scientific and technical problems
Preferred
Have worked with systemically delivered vectors and evaluated their transduction of peripheral tissues
Have worked on expression targeting to specific cell types
Have worked with transgenic mouse models
Have worked with large animal models
Company
Merge Labs
Merge Labs provides a single API to connect software applications with multiple third-party platforms.
Founded in 2025
11-50 employees
Funding
Current Stage
Early StageTotal Funding
$252MKey Investors
OpenAI
2026-01-15Seed· $252M
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