Summit Therapeutics, Inc. · 2 hours ago
Senior Program Manager, Integration and Strategic Outputs
Palo Alto, CA
Full-time
Onsite
Senior Level, Lead/Staff
$174K/yr - $204K/yr
8+ years expSummit Therapeutics Inc. is a biopharmaceutical oncology company focused on improving quality of life and addressing serious unmet medical needs. The Senior Program Manager, Integration & Strategic Outputs is responsible for enabling high-quality execution and integration across the oncology pipeline, driving cross-functional collaboration and ensuring alignment with clinical development objectives.
BiotechnologyHealth CareMedical DeviceTherapeutics
Responsibilities
Drive execution against program-level and corporate milestones, proactively identifying risks, interdependencies, and mitigation strategies
Ensure alignment between functional execution, program strategy, and governance expectations, particularly for Summit-sponsored Phase 2/3 studies
Lead and coordinate complex, cross-functional workstreams tied to corporate goals
Lead program management and facilitation of new indication workstreams to establish and refine study assumptions frameworks, decision gates, and key inputs/outputs required to support downstream execution and portfolio value maximization
Ensure consistency, rigor, and decision quality across indication expansion activities, ISTs, cooperative group studies, and evidence-generation strategies
Develop, maintain, and evolve an integrated portfolio 'source of truth' for ELT and senior leadership, providing visibility across timelines, milestones, risks, and strategic dependencies
Own and continuously enhance ELT-level dashboards and reporting outputs, integrating cross-functional inputs across Clinical, Biomarkers, CMC, Regulatory, and Business Strategy
Ensure portfolio data translates into actionable insights for resource planning, budget forecasting, clinical demand, and clinical supply planning
Design and implement scalable Product/Program level infrastructure, tools, and playbooks that support repeatable, high-quality execution across the portfolio
Develop standardized templates and frameworks, and ensure all processes and tools are documented, governed, and embedded within the PMO library
Partner closely with Clinical Operations, Development, Biometrics, Regulatory, CMC, Legal, Quality, IT, and Commercial teams to ensure integrated execution and decision-making
Support integration of external collaborations like ISTs, Co-op groups into portfolio plans, milestone tracking, and strategic outputs
Ensure clinical development milestones, program dependencies, and portfolio priorities remain aligned and visible
Frame clear problem statements, integrate cross-functional perspectives, assess risks and tradeoffs, and support leadership alignment prior to execution changes
Lead integrated scenario planning for programs to drive critical decisions impacting Summit-sponsored studies
Prepare clear, concise, and decision-ready updates for the Department Heads and ELT, highlighting progress, risks, tradeoffs, and opportunities
Navigate ambiguity with confidence, providing structure, clarity, and momentum in complex environments
Foster strong cross-functional partnerships and act as a trusted thought partner to functional and program leaders
Qualification
Required
Bachelor's degree required (scientific, technical, or business discipline preferred)
8+ years of experience in biopharma, biotechnology, or CRO environments
Direct experience supporting oncology drug development in solid tumors within early development and pivotal programs
Demonstrated experience in program management, Clinical operations and strategic execution
Experience operating in matrixed, fast-growing organizations
Collaborative leader with the ability to influence without authority
Strategic thinking with strong execution discipline
Exceptional communication (written and verbal) and stakeholder management skills
Highly organized, outcomes-driven, and comfortable managing multiple priorities
Strong problem-solving, scenario framing, and decision-support capabilities
Strong proficiency in Smartsheet's, MS Office and dashboarding tools
Solid understanding of clinical development operations
Ability to synthesize complex information into clear strategic insights and executive-level outputs
Preferred
Master's degree preferred
PMP certification preferred
Benefits
Bonus
Stock
Benefits
Other applicable variable compensation
Company
Summit Therapeutics, Inc.
Summit Mission Statement: To build a viable, long-lasting health care organization that assumes full responsibility for designing, developing, trial execution and enrollment, regulatory submission and approval, as well as successful commercialization of patient, physician, caregiver, and societal-friendly medicinal therapy intended to: improve quality of life, increase potential duration of life, and resolve serious medical healthcare needs.
201-500 employees
H1B Sponsorship
Summit Therapeutics, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (3)
2024 (6)
2023 (1)
Funding
Current Stage
Public CompanyTotal Funding
$1.79BKey Investors
CARB-XEurofarmaBiomedical Advanced Research and Development Authority (BARDA)
2025-10-21Post Ipo Equity· $500M
2024-09-11Post Ipo Equity· $235M
2024-06-03Post Ipo Equity· $200M
Leadership Team
Manmeet Soni
Chief Operating Officer and Chief Financial Officer
Recent News
Company data provided by crunchbase