Lumanity · 20 hours ago
Statistician
Boston, MA
Full-time
Hybrid
Mid, Senior Level
3+ years expLumanity is dedicated to improving patient health by accelerating and optimizing access to medical advances. The Patient-Centered Outcomes team is seeking a Statistician to design and execute statistical analyses for patient-reported outcomes and conduct post-hoc analyses of clinical trial data, serving as a trusted advisor to clients and stakeholders.
Market Research
Responsibilities
Design and execute statistical analyses for PRO data in standalone studies
Conduct post-hoc analyses of clinical trial data to uncover additional value in study treatments
Translate complex statistical results into evidence that meets regulatory, clinical, and payer expectations
Serve as a trusted advisor to clients and stakeholders on PRO statistical strategies within drug development pipelines
Design studies using non-interventional data or devise statistical approaches to analyze PROs in interventional studies, enabling robust and meaningful insights
Experience also designing and analyzing Discrete Choice Experiments (DCE) and other stated-preference methodologies (e.g., Best-Worst Scaling, Conjoint Analysis) to quantify patient preferences and inform product development and market access strategies is sought, though not required for this job
Develop detailed statistical analysis plans, execute data analyses, interpret findings, and prepare clear, comprehensive reports
Conduct post-hoc analyses of clinical trial data to identify additional treatment benefits or insights related to PROs
Compile and author statistical sections of COA dossiers, integrating evidence to support regulatory and market access submissions
Maintain strong Sponsor relationships by delivering scientifically rigorous analyses designed to meet client and program needs, balancing methodological precision with practical decision-making
Qualification
Required
Master's degree or higher in Statistics or Biostatistics, with 3–5 years of experience in a life sciences consultancy
Proficiency in methods tailored for skewed, bounded, longitudinal, and missing PRO data, including: Mixed Models for Repeated Measures (MMRM), Analysis of Covariance (ANCOVA), Logistic Regression, Non-parametric tests (e.g., Wilcoxon Rank-Sum), Multiple Imputation or likelihood-based methods for missing data, Sensitivity analyses for post-hoc scenarios
Comprehensive familiarity with frameworks that guide statistical methods for PROs, including: FDA's Patient-Focused Drug Development Guidance Series and disease-specific guidances, HTA Coordination Group JCA Dossier guidance, EMA's Reflection Paper on patient experience data, ICH E9(R1) Statistical Principles for Clinical Trials: Addendum on Estimands and Sensitivity Analysis, FDA's 2017 draft guidance on Estimands in Clinical Trials
Proficiency in R, including packages for longitudinal and categorical data analysis, and the wider tidyverse suite
Experience working in a regulated programming environment
Skilled in preparing statistical analysis plans and technical reports using standardized templates to ensure efficiency and consistency
Exceptional written and verbal communication skills, with the ability to translate complex statistical concepts into clear, actionable insights for diverse audiences
Strong problem-solving abilities and adaptability in fast-paced environments
Skilled in partnering with clients during high-stakes projects, balancing responsiveness with scientific rigor
Proven ability to collaborate respectfully and effectively within cross-functional, mixed-methods research teams
Preferred
Experience designing and analyzing Discrete Choice Experiments (DCE) and other stated-preference methodologies (e.g., Best-Worst Scaling, Conjoint Analysis) to quantify patient preferences and inform product development and market access strategies
Experience leveraging emerging AI tools to scale statistical programming and enhance scientific writing efficiency
Benefits
Medical, dental, and vision insurance options
401(k) plan with employer match
Generous amount of paid time off annually + 10 paid holidays
Flexible spending accounts for health and dependent care
Employee Assistance Program
Paid short-term and long-term disability coverage and more
Company
Lumanity
Lumanity applies incisive thinking and decisive action to cut through complex situations and deliver transformative outcomes.
1001-5000 employees
Funding
Current Stage
Late StageLeadership Team
Denis Getsios
Senior Vice President, Scientific Strategy & Applications
Ed Saltzman
Senior Strategic Advisor
Recent News
2026-01-05
Company data provided by crunchbase