Natera · 15 hours ago
Lead Machine Learning and Bioinformatics Scientist
San Carlos, CA
Full-time
Hybrid
Senior Level, Lead/Staff
$144K/yr - $180K/yr
6+ years expNatera is a global leader in cell-free DNA testing, dedicated to oncology and personalized genetic diagnostics. They are seeking a Lead Machine Learning Scientist to drive innovative research and development in Bioinformatics, particularly focusing on cancer detection and monitoring using advanced machine learning approaches.
BiotechnologyGeneticsHealth DiagnosticsMedicalWomen's
Responsibilities
Design, implement, and validate cutting-edge machine learning and statistical methods to solve problems in cancer diagnostics
Contribute to best practices in model interpretability, uncertainty estimation, and reproducibility
Design robust feature engineering and extraction pipelines tailored to biological data
Prototype and productionize models using scalable ML infrastructure tools such as MLflow, Airflow, and Docker
Collaborate closely with molecular biologists on experimental design, ensuring data integrity and quality control
Foster a culture of innovation, collaboration, and scientific excellence
Actively participate in code and design reviews
Qualification
Required
PhD in Computer Science, Machine Learning, Statistics, Bioinformatics, or a related quantitative field with a strong emphasis on cancer epi/genomics and 6+ years of experience post-PhD
Deep expertise in the theory and practical development of core machine learning models, including generalized linear models, kernel methods, tree-based algorithms, and neural networks, with a focus on biological data (e.g., DNA/RNA sequencing data)
Proficiency in Python and its scientific computing stack (e.g., NumPy, Pandas, Scikit-learn)
Strong cross-functional communication skills, with the ability to collaborate effectively across disciplines
High scientific rigor and a growth mindset, with enthusiasm for both teaching and learning new computational and biological concepts
Preferred
Hands-on experience with state-of-the-art deep learning models, large language models (LLMs), and multimodal foundation models
Benefits
Annual performance incentive bonus
Long-term equity awards
Comprehensive health benefits (medical, dental, vision)
401(k) with company match
Generous paid time off and company holidays
Additional wellness and work-life benefits
Comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents
Free testing in addition to fertility care benefits
Pregnancy and baby bonding leave
401k benefits
Commuter benefits
Generous employee referral program
Company
Natera
Natera specializes in cell-free DNA testing to provide a more targeted interventions to oncology, women's health, and organ health.
5001-10000 employees
H1B Sponsorship
Natera has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (90)
2024 (72)
2023 (37)
2022 (71)
2021 (64)
2020 (40)
Funding
Current Stage
Public CompanyTotal Funding
$1.16BKey Investors
Sofinnova InvestmentsLightspeed Venture PartnersSequoia Capital
2023-09-07Post Ipo Equity· $250M
2022-11-15Post Ipo Equity· $400.05M
2022-03-16Post Ipo Equity· $5M
Leadership Team
Steve Chapman
CEO
Jonathan Sheena
Co-Founder, Board Member
Recent News
2026-01-22
Business Wire
2026-01-22
Company data provided by crunchbase