Keros Therapeutics · 9 hours ago
Senior Research Associate I, In Vivo
Lexington, Massachusetts, United States
Full-time
Onsite
Mid, Senior Level
$96K/yr - $108K/yr
4+ years expKeros is a company focused on delivering clinical benefits through innovative therapeutics targeting TGF-β signaling. They are seeking a motivated Senior Research Associate I to contribute to the development of novel therapeutics for rare diseases, primarily through preclinical research in areas such as neuromuscular and neurodegenerative disorders.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Design, execute and manage complex experiments and research projects with minimal supervision, including evaluation of efficacy, pharmacokinetics, pharmacodynamics, tolerability, and mechanism of action of drug candidates
Perform basic animal handling, including dosing, (IP, IV, SC, PO, IT, OA), blood and tissue collection, necropsy, and small animal surgeries
Ex vivo processing of tissues for further characterization, including RNA isolation for qPCR, protein lysates for Western blots or ELISA, single cell suspensions for flow cytometry and cryo-sectioning tissues for immunohistochemistry
Analyze and interpret experimental data, troubleshoot technical challenges and optimize protocols
Collaborate closely with team members to align experimental work with broader research goals
Contribute to the drafting of reports and presentations for internal and external communication, including publications and regulatory documents
Mentor and train junior research associates/co-ops, providing guidance on experimental design, data analysis, and best laboratory practices
Ensure laboratory operations comply with all safety regulations, standard operating procedures (SOPs) and quality control standards
Contribute to the maintenance, calibration, and use of laboratory equipment and efficient operation of the laboratory
Stay current with the latest scientific literature and technological advancements, incorporating new knowledge into research activities, particularly in preclinical in vivo models
Participate and contribute to scientific discussions on project direction and objectives
Maintain detailed records in electronic lab notebook (ELN)
Qualification
Required
Bachelor's degree in Biology or related field with 4+ years of experience or Master's degree with 2+ years of experience
Experience working with and developing rodent disease and mechanistic models and running pharmacokinetic and pharmacodynamic experiments, including dosing, (IP, IV, SC, PO, IT, OA), blood and tissue collection, necropsy, and small animal surgeries
Extensive experience with a wide range of wet laboratory techniques, including qPCR, Western blotting, ELISA, flow cytometry and immunohistochemistry
Strong problem-solving skills, with a track record of successfully troubleshooting and optimizing experimental protocols
Excellent data analysis skills, with proficiency in data analysis software and experience with statistical analysis
Proven ability to mentor and train junior team members, fostering a collaborative and productive laboratory environment
Strong organizational and project management skills, with the ability to manage multiple projects and deadlines
Strong communication skills, both written and verbal, with experience in preparing technical reports, scientific publications and presentations
Preferred
Demonstrated ability to independently design, execute, and manage complex experiments and research projects
Experience with electrophysiology or histological analysis/image processing for muscle or nervous system
Research experience in the field of muscle and/or neurobiology
Company
Keros Therapeutics
Keros is a clinical-stage biopharmaceutical company focusing on the discovery, development, and commercialization of novel treatments.
51-200 employees
H1B Sponsorship
Keros Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (2)
2023 (1)
2022 (3)
2021 (1)
Funding
Current Stage
Public CompanyTotal Funding
$379.5MKey Investors
Pontifax
2024-01-03Post Ipo Equity· $140M
2020-11-13Post Ipo Equity· $149.5M
2020-04-07IPO
Leadership Team
Lorena Lerner
Chief Scientific Officer
Recent News
Keros Therapeutics, Inc.
2025-11-21
2025-11-20
Keros Therapeutics, Inc.
2025-11-19
Company data provided by crunchbase