Keros Therapeutics · 19 hours ago
Process Development Associate II
Lexington, MA
Full-time
Onsite
Entry, Mid Level
$79K/yr - $91K/yr
2+ years expKeros Therapeutics is dedicated to delivering clinical benefits to patients with disorders linked to dysfunctional TGF-β signaling. The Process Development Associate II will support early-stage process development and work with Research and CMC organizations, focusing on optimizing and scaling cell lines and processes for biologics manufacturing.
BiotechnologyHealth CarePharmaceuticalTherapeutics
Responsibilities
Understanding of critical process parameters, and developing robust, industrial processes for cell culture production of protein derived from mammalian cell lines for cGMP implementation
Experience with and cell culture scale up/down and process characterization
Experience delivering material suitable for toxicology studies to support regulatory filings
Performing and and operation of protein expression including cell culture from microplate to , familiarity with cell banking, comprehension of manufacturing processes (specifically batch and fed-batch) and harvest of material at required scales
Data analysis and authoring key documents such as development reports
Participating in cross-functional project teams and communicating data, results, and conclusions to scientists, project management, business development, and other stakeholders
Execute routine scale down protein expression using benchtop bioreactors to optimize protein expression processes
Perform, develop and optimize robust, efficient, scalable strategies for improving process performance
Activities will include small-scale studies and pilot scale expression studies
Apply DOE methods to expression activities
Mentoring Co-Ops and helping them in their planning and activities
Maintain laboratory notebooks and digital records
Present data at process development and CMC department meetings
Qualification
Required
B.S. in Biology, Biochemistry, Biomedical Engineering, or an equivalent engineering/science degree with 2-5 years of experience working in the Biopharma industry
Strong hands-on experience in troubleshooting and routine instrument maintenance
Upstream processes at the small to an intermediate scale of cGMP biologics production
Process scaling and/or technology transfer
Authoring and executing protocols, interpretation of data, and report generation
Operating and troubleshooting process equipment
Ability to work independently and as part of a cross-functional team
Ability to adapt to frequent change and thrive in a dynamic early-stage environment
Strong communication and organization skills, strong knowledge of MS Office, data plotting and graphing software. Must be able to communicate results effectively
Preferred
Experience using electronic lab notebooks
Company
Keros Therapeutics
Keros is a clinical-stage biopharmaceutical company focusing on the discovery, development, and commercialization of novel treatments.
51-200 employees
H1B Sponsorship
Keros Therapeutics has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2024 (2)
2023 (1)
2022 (3)
2021 (1)
Funding
Current Stage
Public CompanyTotal Funding
$379.5MKey Investors
Pontifax
2024-01-03Post Ipo Equity· $140M
2020-11-13Post Ipo Equity· $149.5M
2020-04-07IPO
Leadership Team
Lorena Lerner
Chief Scientific Officer
Recent News
Keros Therapeutics, Inc.
2025-11-21
2025-11-20
Keros Therapeutics, Inc.
2025-11-19
Company data provided by crunchbase