Legend Biotech · 11 hours ago
Scientist
Philadelphia, PA
Full-time
Hybrid
Mid Level
$107K/yr - $141K/yr
3+ years expLegend Biotech is a global biotechnology company dedicated to treating life-threatening diseases. They are seeking a highly motivated and creative Scientist II to join their R&D Novel Car Design team, focusing on the research and development of next-generation cell therapies using innovative in vivo gene delivery technologies.
BiotechnologyHealth CareLife ScienceOncologyTherapeutics
Responsibilities
Be able to work independently under minimal supervision
Lead, design and optimize research with aims of exploring next generation cell therapies using in-vivo CAR virus
Perform functional characterization of T cells transduced with in-vivo CAR virus using multiple functional assays but not limited to cytotoxicity assay, serial cytotoxicity assay, and cytokine release assay etc
Help execute the evaluation of in-vivo CAR virus using in-vitro assays and in-vivo mice models
Design, execute and interpret research requiring molecular biology techniques including PCR/DDPCR/qPCR, NGS, RNA and DNA analysis
Perform research requiring cell biology techniques including cell culture, transfection, FACS, and cellbased assays
Analyze and present data to a wide range of audiences of internal group meetings and other forums
Dissect published literature to find novel solutions to in-vivo cell therapy problems
Generate, manage, evaluate, and maintain critical data in a highly organized manner
Qualification
Required
PhD in Biology or related discipline
3 years of experience in the field of cell therapy with cell culture methods (T cells, CAR-T or TCR-T preferred), quantitative PCR and functional characterization of T cells (Cytotoxicity assay using Incucyte or xCelligence, and MLR assay)
Proficient in cell-based assays with various read out technologies such as flowcytometer, Incucyte, Xcelligence
Experience with transfection and lentivirus or retrovirus transduction
Experience/ working knowledge (molecular biology and cellular biology) in design and evaluation of modified viruses
Individual should be go-getter and be able to work independently
Excellent written and oral communication skills
Preferred
Prior experience with in-vivo CAR virus evaluation will be preferred
Benefits
Medical, dental, and vision insurance
401(k) retirement plan with a company match that vests fully on day one
Eight (8) weeks of paid parental leave after just three (3) months of employment
Paid time off policy that includes vacation time, personal time, sick time, floating holidays, and eleven (11) company holidays
Flexible spending and health savings accounts
Life and AD&D insurance
Short- and long-term disability coverage
Legal assistance
Supplemental plans such as pet, critical illness, accident, and hospital indemnity insurance
Commuter benefits
Family planning and care resources
Well-being initiatives
Peer-to-peer recognition programs
Company
Legend Biotech
Legend Biotech is a biopharmaceutical company that develops and commercializes novel cell therapies for oncology.
1001-5000 employees
H1B Sponsorship
Legend Biotech has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (30)
2024 (11)
2023 (14)
2022 (7)
2021 (6)
2020 (13)
Funding
Current Stage
Public CompanyTotal Funding
$750.45M2023-05-05Post Ipo Equity· $350M
2022-07-25Post Ipo Equity· $250M
2020-06-05IPO
Leadership Team
Carlos Santos
Chief Financial Officer
Alan Bash
President, CARVYKTI
Recent News
legacy.thefly.com
2026-01-22
2026-01-22
Company data provided by crunchbase