Dyne Therapeutics · 10 hours ago
Medical Director, US Medical Affairs
Waltham, MA
Full-time
Onsite
Director/Executive
$196K/yr - $285K/yr
8+ years expDyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. The US Medical Director of Medical Affairs leads the company's medical strategy and execution within the United States, focusing on launch readiness, KOL engagement, and real-world evidence initiatives.
BiotechnologyHealth CareMedicalPharmaceutical
No H1B
Responsibilities
Develop and execute US Medical Affairs strategy aligned with global objectives and US market needs
Act as point person for all US Medical Affairs launch readiness activities, including working closely with global medical director and scientific communications on development of scientific platform development, local congress planning, and local medical education programs
Support congress strategy execution in the US, including booth activities, symposia, and scientific presentations
Work closely and with the Head of the Medical Science Liaison (MSL) team on US KOL engagement strategy: identify, map, and build relationships with key US experts
Support insight collection and synthesis, and supporting the development of field material, working with the MSL team
Develop US Medical Affairs advisory board strategy and organize and execute advisory boards and expert panels
Work collaboratively with HCP and Patient Marketing as well as cross-functional stakeholders to integrate medical perspectives into brand strategy, ensuring alignment with scientific and commercial objectives
Partner with Clinical Development and Clinical Operations to support US trial site engagement and recruitment strategies
Working with the Global Medical Director, identify opportunities to generate real-world evidence (RWE) and phase IV data to address data gaps and support HCP and payer treatment decisions
Ensure compliance with US regulatory and legal requirements for all medical activities
Serve as subject matter expert on neuromuscular diseases and Dyne’s therapeutic platforms for US stakeholders
Support the review and approval of externally presented materials through the Medical Review committee and Promotional Review Committee
Act as a role model for integrity and compliance in all interactions
Qualification
Required
Doctorate degree (MD, PhD, PharmD) with experience in rare diseases
Minimum 8 years of relevant experience in Medical Affairs within the US pharmaceutical/biotech industry
Proven ability to lead US launch readiness and medical strategy execution
Excellent communication and relationship-building skills with US KOLs and cross-functional teams
Ability to interpret and communicate complex scientific data to diverse audiences
Effective communication skills (written, verbal and presentation)
Must be willing to travel up to 30%, inclusive of overnight and occasional weekends to meet with customers, internal stakeholders and attend relevant conferences
Candidates must be authorized to work in the U.S
Positive team member who embodies Dyne's Core Values
Excitement about Dyne's vision and mission
Experience managing direct reports
Preferred
neuromuscular experience preferred
Company
Dyne Therapeutics
Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.
51-200 employees
Funding
Current Stage
Public CompanyTotal Funding
$1.67BKey Investors
Hercules CapitalAtlas Venture
2025-12-09Post Ipo Equity· $402.5M
2025-06-30Post Ipo Equity· $230M
2025-06-30Post Ipo Debt· $100M
Leadership Team
John Cox
Chief Executive Officer
Recent News
2026-01-11
2026-01-07
Company data provided by crunchbase