GSK · 17 hours ago
Director, Translational Lead Respiratory
Collegeville, PA
Full-time
Hybrid
Director/Executive
$190K/yr - $316K/yrGSK is a global biopharma company aiming to positively impact the health of 2.5 billion people by the end of the decade. They are seeking a Director, Translational Lead Respiratory to provide strategic leadership in developing and executing translational research strategies, focusing on biomarker development and collaboration across various teams to enhance drug development processes.
BiotechnologyHealth CarePharmaceutical
Responsibilities
Partner with the Clinical Teams, Research Technologies and the Development organization with focus on Respiratory portfolio to identify, establish biomarkers for decision making throughout clinical development phases and aligned with the overall research and development goals. This will include the identification, prioritization and validation of disease relevant biomarkers, mechanistic/surrogate biomarkers, patient stratification, and differentiated response prediction, their deployment into clinical studies and interpretation of data/results
Provide strategic leadership contributing to deep understanding of Disease areas enabling the development and execution of translational research disease strategies to support the discovery and development of novel differentiated therapeutics including evaluation and diligence of business development opportunities
Evaluate novel techniques and technologies (i.e. spatial transcriptomics) to inform translational initiatives, biomarker development and validation working in collaboration with platform teams and within a multi-functional matrix environment
Identify and guide validation of human assays (cells, tissues and organs) to enhance human translation and predictive value through the application of resources such as the Human Cell Atlas, disease tissue multi-omics data and genetic resources (external or proprietary)
Collaborate closely with cross-functional teams including the Translational, Disease Teams, Human Genetics & Genomics, biology groups, biomarker platforms, Medicine Development Teams, HBSM, data-sciences, regulatory affairs, business development and commercial to ensure seamless integration of translational research and biomarker strategies across the drug development lifecycle
Establish and maintain strategic collaborations with academic institutions, contract research organizations (CROs), and other external partners to access cutting-edge technologies, tools, reagents, biosamples, biomarker expertise, and research capabilities. o Foster a network of external experts and key opinion leaders to stay at the forefront of translational science and biomarker advancements across the industry
Contribute to evaluation and diligence of business development opportunities
Provide mentorship, guidance, and professional development opportunities to ensure a high-performing and motivated team
Manage disease and project level resources, budgets, and timelines to ensure the successful execution of projects and achievement of milestones and RITU objectives
Represent RITU at portfolio governance reviews providing critical input to pipeline and investment decision making
Qualification
Required
Ph.D. in a relevant scientific discipline (e.g., Cell/Molecular Biology, Genetics, Pharmacology, Physical Chemistry or related field)
Extensive experience in translational science and biomarker development ideally within the pharmaceutical or biotechnology industry
Recognised translational/biomarker expert in scientific community through publications and contributions to the field
Experience of translation and biomarkers implementation in Respiratory indications
Experience of working in a clinical trial setting, working as part of a clinical study and experience of authoring and oversight of clinical and regulatory documents
Preferred
Knowledge of regulatory requirements, industry standards, best practices and compliance considerations in Translational Research and biomarker development and validation
Broad knowledge in technologies and methods used in translational research
Proven track record of program decision making through implementing biomarker strategies and delivering translational science insights in support of drug progression through clinical transition milestones
Experience leading/managing external collaborations and evaluation of business development opportunities
Strong management skills, with the ability to prioritize and manage multiple objectives to meet timelines while maintaining attention to detail and high-performance standards
Excellent inclusive matrix leadership skills, with the ability to create psychological safety, inspire and motivate a team towards achieving common goals
Benefits
Annual bonus
Eligibility to participate in our share based long term incentive program which is dependent on the level of the role
Health care and other insurance benefits (for employee and family)
Retirement benefits
Paid holidays
Vacation
Paid caregiver/parental and medical leave
Company
GSK
We are uniting science, technology and talent to get ahead of disease together. Our community guidelines: https://gsk.to/socialmedia
Founded in 1929
10001+ employees
H1B Sponsorship
GSK has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (45)
2024 (56)
2023 (54)
2022 (53)
2021 (54)
2020 (72)
Funding
Current Stage
Public CompanyTotal Funding
$25.51MKey Investors
CARB-X
2021-03-02Grant· $18M
2020-09-23Grant· $7.51M
1978-01-13IPO
Leadership Team
Julie Brown
CFO
Mike Elmore
SVP & Chief Information Security Officer, GSK
Recent News
2026-01-16
2026-01-13
South China Morning Post
2026-01-08
Company data provided by crunchbase