Vaxcyte · 10 hours ago
Associate Scientist II (Contract), Research
San Carlos, California, United States
Contract
Onsite
Entry, Mid Level
$51/hr - $56/hr
2+ years expVaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from bacterial diseases. They are seeking an Associate Scientist II (contract), Research, to support the research and development of a novel bacterial polysaccharide conjugate vaccine, contributing to various laboratory processes and optimization initiatives.
BiopharmaBiotechnologyHealth Care
Responsibilities
Set up, optimize, and troubleshoot multi-step syntheses of protein-polysaccharide conjugates using click-chemistry and other related chemistries
Purify polysaccharides and conjugates using a variety of methods, including dialysis, FPLC chromatography, and tangential flow filtration (TFF)
Characterize protein/polysaccharide/conjugates using different analytical methods, including SDS-PAGE gel, Western blotting, ELISA, HPLC, SEC-MALS, colorimetric and dynamic binding assays, et al
Apply Design of Experiments (DoE) principles; design, execute, and interpret statistically modeled experiments using DoE software
Proactively contribute scientific ideas, experimental strategies, and process improvements
Independently review and summarize relevant scientific literature to inform experimental design
Maintain highly organized records and Benchling entries to enable optimization and assessment of reproducibility
Analyze, interpret, and clearly communicate experimental data, including identifying trends, anomalies, and recommending next steps
Execute established protocols with limited oversight, demonstrating strong technical proficiency
Support team in routine laboratory activities and instrument maintenance
Qualification
Required
BS. in Chemistry, Biochemistry, or related field or a related discipline, with minimum 2 years of relevant industry experience. MS without experience; or equivalent work experience
Strong understanding of underlying scientific concepts, process development, and analytical assay principles
Extensive hands-on experience in purification methods such as diafiltration, depth filters, and TFF (required)
Proficiency with common protein/polysaccharide/conjugates analytical techniques, including SDS-PAGE, Western blotting, ELISA, HPLC, and SEC-MALS, is required
Proven track record of developing scalable processes suitable for the pharma/Biotech industry
Attention to detail and excellent organizational skills
Ability to contribute to the overall lab management, including organization of vendors, service contracts, and equipment maintenance
Demonstrated success working in a cross-functional team environment
Strong interpersonal skills, with excellent written and verbal communication skills
Preferred
Prior hands-on experience in the conjugation process development is highly desirable
Experience with vaccines, carbohydrates, or protein is a plus
Company
Vaxcyte
Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.
201-500 employees
H1B Sponsorship
Vaxcyte has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2024 (7)
2023 (5)
2022 (7)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$3.85BKey Investors
CARB-XTPG GrowthAbingworth
2024-09-04Post Ipo Equity· $1.5B
2024-01-30Post Ipo Equity· $862.5M
2023-04-19Post Ipo Equity· $500M
Leadership Team
Andrew Guggenhime
President & Chief Financial Officer
Jeff Fairman
Founder and Vice President, Research
Recent News
Pharma Letter
2026-01-25
2026-01-23
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