Gilead Sciences · 6 hours ago
Sr Director, Drug Metabolism
San Francisco Bay Area
Full-time
Onsite
Director/Executive
$261K/yr - $338K/yr
14+ years expGilead Sciences is a research-based biopharmaceutical company dedicated to creating innovative medicines for unmet medical needs. They are seeking a Senior Director of Drug Metabolism and Pharmacokinetics (DMPK) to provide expert support in pharmacokinetics for biologics discovery and development projects, collaborating with various teams to ensure high-quality regulatory submissions.
BiopharmaBiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Serve on project teams at various stages of discovery and development as a subject matter expert for DMPK Biologics, providing PK or PK/PD expertise to the design of nonclinical PK, toxicology, or pharmacology studies
Prepare study protocols and coordinate execution of nonclinical studies which may involve multiple functional areas and CROs
Design and perform complex PK-PD analysis to answer translational questions in support of project deliverables and first-in-human dose predictions
Interpretation and strategy for evaluating the impact of anti-drug antibody (ADA)
Participate in business development and licensing evaluations
Work closely with project teams, line management and CROs to assure high quality and timely delivery of written PK reports and regulatory documents (IND, IMPD, IB, BLA) for regulatory submissions
Supervising of research scientists and associate scientists may be required
Qualification
Required
PhD and 14+ years of post-graduate industry experience in the fields of pharmacokinetics, drug metabolism, pharmaceutics, or related life science field primarily supporting the PK characterization of large molecule/biologics through discovery and development
Excellent verbal and technical communication skills
Independent scientific thinking with the ability to interpret results, determine next steps and present data to project teams and senior management
Intellectual curiosity and propensity to stay current with latest advances in DMPK of biologics and PK analysis
Proven track record of sustained external visibility through publications, presentations and/or involvement in professional organizations
Highly experienced in the application of PK-PD and multi-compartmental modeling software systems such as Phoenix/WinNonlin, MATLAB/Simbiology, or similar
Preferred
Knowledge in the application of large molecule/biologics ligand binding assays and LC/MS bioanalysis
Benefits
Discretionary annual bonus
Discretionary stock-based long-term incentives (eligibility may vary based on role)
Paid time off
Company-sponsored medical, dental, vision, and life insurance plans
Company
Gilead Sciences
Gilead Sciences is a biopharmaceutical company that discovers, develops, manufactures and commercializes therapies for critical diseases.
10001+ employees
H1B Sponsorship
Gilead Sciences has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (269)
2024 (241)
2023 (222)
2022 (208)
2021 (235)
2020 (187)
Funding
Current Stage
Public CompanyTotal Funding
$4.41BKey Investors
Abingworth
2024-11-13Post Ipo Debt· $3.5M
2024-02-29Post Ipo Equity· $210M
2023-09-07Post Ipo Debt· $2B
Leadership Team
Keeley Wettan
Senior Vice President, Legal
Patrick Loerch
Senior Vice President, Clinical Data Science
Recent News
2026-01-23
GlobeNewswire
2026-01-22
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