CHEManager International · 23 hours ago
Senior Research Associate - in vivo
Alameda, CA
Full-time
Onsite
Mid, Senior Level
$82K/yr - $123K/yrE11 Bio is a non-profit Convergent Research focused research organization located in Alameda, California, pursuing blue-skies neuroscience research. They are seeking a hands-on in vivo senior technician to take full ownership of animal perfusions and in vivo workflows, ensuring the reliability and reproducibility of tissue used for brain mapping.
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Responsibilities
Take ownership of all animal perfusions, including preparation of perfusates, execution of procedures, troubleshooting tissue-quality issues, and continuous improvement of fixation protocols
Execute and support in vivo surgical workflows, including stereotaxic and retro-orbital viral injections, post-operative monitoring, and animal welfare documentation
Apply scientific training to monitor, control, and systematically optimize key in vivo and perfusion parameters for tissue labeling + preservation
Collaborate closely with experimental scientists to design, execute, and troubleshoot in vivo labeling experiments, contributing technical judgment and experimental insight
Perform routine animal health checks and husbandry tasks as needed, with attention to health or behavioral changes that may impact experimental outcomes
Maintain accurate experimental records, reproducible protocols, and operational readiness of perfusion and surgical equipment
Contribute to a positive, collaborative lab culture and run small, focused experimental projects
Qualification
Required
Hands-on experience performing animal perfusions using PFA or related fixatives for neuroscience or brain tissue applications, with the ability to produce consistent, high-quality tissue
Demonstrated ability to quickly learn, independently own, and optimize complex biological workflows, including diagnosing and resolving tissue-quality or protocol failures
Experience with rodent handling, restraint, and basic health assessment in a research setting
Strong record of reliability, precision, and careful experimental documentation
Clear communication skills and a proven ability to collaborate effectively within interdisciplinary research teams
Preferred
Mechanical or technical aptitude for maintaining, adjusting, or troubleshooting perfusion rigs, surgical setups, and related laboratory hardware
Experience with in vivo surgical techniques such as stereotaxic or retro-orbital viral injections (or strong interest and aptitude to train into these methods)
Familiarity with downstream histology, imaging, or molecular tissue workflows
Interest in neuroscience and connectomics, with motivation to contribute to technically demanding, high-impact research
Benefits
Excellent medical, dental, and vision insurance through a PPO plan; parental leave.
401K match to 6%
Generous time off + paid holidays.
Ample healthy and energizing food including daily lunches.
Wellness allowance for fitness and wellness activities.
Company
CHEManager International
Wiley’s leading media brand providing first-hand information on the global chemical, life science and process industries
201-500 employees
Funding
Current Stage
Growth StageCompany data provided by crunchbase