SystImmune · 15 hours ago
Scientist/ Research Associate – AI Protein Design
Redmond, WA
Full-time
Onsite
Senior Level, Lead/Staff
$80K/yr - $180K/yr
8+ years expSystImmune is a leading and well-funded clinical-stage biopharmaceutical company specializing in developing innovative cancer treatments. They are seeking a creative and motivated individual to execute and improve their Computational Protein Design pipeline, focusing on designing novel peptides and proteins using data-driven approaches.
BiopharmaBiotechnologyProfessional Services
Responsibilities
Execute a computational design pipeline for predicting the properties of peptides, natural ligands, de novo proteins, and antibody-based elements via data-driven approach
Drive assay validation, tech transfer, and development initiatives to maintain industry standards; Contribute within the computational protein design group to operate yeast display-based protein discovery platforms
Design new macromolecular therapeutics using structural and sequence analysis, and employ these in silico predictions to iteratively guide the lead development process
Analyze, interpret, document, and present data to the scientific and leadership team
Collaborate with our Antibody Discovery, Protein Engineering, and Immuno-oncology teams to contribute to the company's vision
Qualification
Required
PhD (or equivalent) in bioengineering, biophysics, biochemistry, molecular biology, cell biology, or a related field
8+ years of experience using yeast libraries to generate protein binding or therapeutic antibodies required
Experience with relevant macromolecular modeling software (e.g., AlphaFold, RoseTTAFold, RFdiffusion, ProteinMPNN, Gromacs, MOE, Schrödinger)
Expertise in screening and ranking of antibodies (ELISA, multi-parametric flow cytometry, BLI/OCTET)
Preferred
Proven contribution to therapeutic antibody development and selection is desirable
Design and validation of novel biologically relevant antibodies are highly desirable
Benefits
100% paid employee premiums for medical/dental/vision
STD
LTD
401(k) plan with a 50% company match of up to 3%
Vesting schedule of only 5 years
15 PTO days per year
Sick leave
11 paid holidays
Company
SystImmune
SystImmune is a biotechnology company.
51-200 employees
H1B Sponsorship
SystImmune has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2023 (1)
2022 (2)
2021 (2)
2020 (1)
Funding
Current Stage
Growth StageLeadership Team
Martin S. Olivo, MD, MSc,
Chief Medical Officer
Recent News
Company data provided by crunchbase