AbbVie · 19 hours ago
Scientist II, Biologics Drug Substance Development, Cell Culture Development
South San Francisco, CA
Full-time
Onsite
Mid, Senior Level
5+ years expAbbVie is dedicated to discovering and delivering innovative medicines and solutions that address serious health issues. The Scientist II will develop cell culture processes for GMP applications and support the advancement of novel biotherapeutics into human clinical studies.
BiotechnologyFinancial ServicesHealth CareMedicalPharmaceuticalVenture Capital
Responsibilities
Develop and optimize robust and scalable cell culture processes in ambr250 and 2L bioreactors
Perform pilot scale material generation using 50L, 200L and 500L single use bioreactors
Develop inoculum expansion and master cell bank generation processes
Design and execute small scale and pilot scale depth filtration and centrifugation primary recovery processes
Perform tech transfer of Master cell bank generation, cell culture and primary recovery processes to the GMP manufacturing facilities
Provide person-in-plant support at the GMP manufacturing facility
Develop and optimize N-1 perfusion processes as well as intensified fed-batch processes
Represent the cell culture development group in cross-functional meetings and collaborate closely with cell line, purification, analytical and formulation development leads to meet project timelines
Author and review technical reports, GMP campaign summary reports and relevant sections in regulatory filings
Proactively identify and implement opportunities to optimize platform processes and deepen process understanding
Present scientific findings at internal or external conferences
Qualification
Required
Scientific degree in chemical engineering, bioengineering, biotechnology, or a related field, ≥ 5 years for M.S., or ≥ 7 years for B.S
Proficient in aseptic techniques
Experienced in developing and executing mammalian suspension cell culture processes in shake flasks, ambr250 and 2L bioreactors
Significant experience with perfusion technology, especially Alternating Tangential flow filtration (ATF) at bench and pilot scale
Strong understanding of mammalian cell and molecular biology and cell culture bioprocess engineering concepts
Strong attention to detail; active and quick learner; able to change courses quickly as needed, raises the bar and is never satisfied with the status quo; open to suggestions and embraces the ideas of others; collaborative actively builds relationships with others
Experienced in technical report authoring and reviewing
Proficient with Microsoft Office software (Word, Excel, and PowerPoint) and statistical modelling software such as JMP
Preferred
Experience with authoring peer-reviewed publications, technical reports, regulatory documents, and/or presentations at conferences
Basic knowledge of automation and coding languages (Python, etc.)
Benefits
Paid time off (vacation, holidays, sick)
Medical/dental/vision insurance
401(k)
Short-term incentive programs
Company
AbbVie
AbbVie is a biopharmaceutical company focused on immunology, oncology, neuroscience, virology, and aesthetics. It is a sub-organization of AbbVie.
10001+ employees
H1B Sponsorship
AbbVie has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (273)
2024 (190)
2023 (225)
2022 (284)
2021 (186)
2020 (186)
Funding
Current Stage
Public CompanyTotal Funding
$15B2024-02-27Post Ipo Debt· $15B
2023-03-08Post Ipo Equity· $0.25M
2012-12-20IPO
Leadership Team
Robert Michael
Chairman of the Board and Chief Executive Officer
Micah Bregman
Vice President, Global Strategy and Pipeline, Allergan Aesthetics
Recent News
2026-01-23
2026-01-20
2026-01-20
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