Insmed Incorporated · 23 hours ago
Senior Scientist
New Hampshire, United States
Full-time
Onsite
Mid, Senior Level
$127K/yr - $166K/yr
4+ years expInsmed Incorporated is a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases. They are seeking a highly experienced biologist, virologist, or bioengineer to lead discovery and engineering initiatives aimed at developing next-generation gene therapies for rare diseases.
BiotechnologyMedicalPharmaceutical
Responsibilities
Lead biological engineering projects focused on development of next-generation viral vectors
Independently design, optimize, and execute high-throughput molecular and cellular screening systems to identify and characterize novel viral capsids
Support viral vector projects, including transfection, transduction, viral titering, and sequencing-based characterization of viral genomes
Implement advanced molecular biology methods to design and build high diversity viral vector libraries
Design, optimize, and execute molecular biology workflows, including DNA/RNA extraction, cloning and PCR/qPCR/ddPCR
Prepare Next-Generation Sequencing (NGS) libraries (Illumina, Nanopore, PacBio) and perform quality measurements (qubit, tape station)
Perform cell culture with mammalian cell lines and primary cells
Design, conduct, and support in vivo studies
Document protocols, write reports, and present findings to cross-disciplinary teams
Contribute to laboratory operations, including training of junior staff and maintenance of high-quality research standards
Qualification
Required
PhD in cell biology, virology, immunology, molecular biology, bioengineering, or related field with 4+ years of relevant industry experience or MS with 8+ years of relevant hands-on experience
Direct report or small team management experience strongly preferred
Proven track record in method development, including experimental design, optimization, execution, and evaluation
Experience with viruses or viral vectors including AAV
Experience with viral transfection, transduction, ultracentrifugation purification (CsCl, iodixanol), genome titer (by qPCR, ddPCR, RT-qPCR, RT-ddPCR) and characterization
Experience with viral vector engineering (large library preparation and screening)
Experience working with mammalian cell lines and primary cells
Hands-on in vivo model or study management experience
Experience with cell-based functional assays including but not limited to ELISpot, ICS, flow cytometry, antibody-neutralization assays, and potency assays
Strong written and oral communication skills
Applicants should be detail-oriented, highly organized, and able to multi-task with multiple projects
Strong analytical and problem-solving skills a must
Preferred
Background in advanced molecular biology methods including cloning and recombinant DNA technologies (DNA/RNA extraction, primer/probe design, PCR/qPCR/ddPCR, Gibson Assembly, Golden Gate etc.)
Proficiency in NGS technologies (Illumina, Nanopore, PacBio), library preparation, and quality assessment (qubit, tape station)
Experience with protein characterization methods, including but not limited to ELISA, SDS-PAGE, western blot, TFF, and affinity chromatography
Benefits
Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back
Company
Insmed Incorporated
Insmed is a people-first global biopharmaceutical company striving to deliver first- and best-in-class therapies to transform the lives of patients facing serious diseases.
1001-5000 employees
H1B Sponsorship
Insmed Incorporated has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (20)
2024 (6)
2023 (14)
2022 (8)
2021 (1)
2020 (5)
Funding
Current Stage
Public CompanyTotal Funding
$4.56BKey Investors
CureDuchenne Ventures
2025-06-11Post Ipo Equity· $750M
2024-05-30Post Ipo Equity· $650M
2023-05-08Post Ipo Equity· $0.5M
Leadership Team
Will Lewis
Chairman and Chief Executive officer
Walter R. Perkins
Chief Technology Officer
Recent News
2026-01-13
Company data provided by crunchbase