Vertex · 21 hours ago
Senior Director, Biomarkers (Immunology)
Seattle, WA
Full-time
Hybrid
Director/Executive
$217K/yr - $325K/yr
11+ years expVertex is a global biotechnology company that invests in scientific innovation, and they are seeking a Senior Director of Biomarkers in Immunology. This role involves leading the biomarker strategy across the immunology portfolio, overseeing assay development, and mentoring a diverse biomarker team while collaborating with cross-functional stakeholders.
Computer Software
Responsibilities
Leads the development and execution of biomarker strategies in alignment with cross-functional stakeholders and senior management, with a focus on immunology and autoimmune disease programs
Oversees assay development, validation, and execution of biomarker assays across various platforms (e.g., flow assays, immunoassays, genomic assays, NGS, imaging biomarkers) at CROs and internally, providing guidance on data analysis and interpretation
Translates preclinical discoveries into clinical biomarker strategies, identifying mechanism-relevant biomarkers to support drug tailoring hypotheses
Manages and mentors a diverse biomarker team, ensuring alignment of best practices across global sites, including PreClinical Sciences (PCS), Research, Translational, Clinical Development, Clinical Operations, and Bioinformatics teams to ensure robust biomarker strategy execution
Serves as a key liaison with internal and external stakeholders, including diagnostic vendors and scientific partners
Effectively communicates complex biomarker strategies to cross-functional teams and senior leaders
Demonstrates advanced scientific expertise in immunology, biomarker development, and translational medicine
Possesses a strong understanding of the drug development process and showcases enterprise thinking. Experience with late-stage program development is highly preferred
Brings strategic agility and late-stage program experience to adapt to emerging trends in biomarker development
Collaborates across business areas and diverse functional stakeholders to successfully meet project deliverables
Qualification
Required
PhD in Immunology, Biochemistry, Molecular Biology, Molecular Pharmacology or related field and 11+ years of experience, or
Master's degree and 15+ years of relevant employment experience, or
Bachelor's Degree and 20+ years of relevant employment experience
Typically requires 5+ years of managing experience
Demonstrated ability to translate preclinical biomarkers into clinical application
Advanced scientific knowledge in immunology, biomarker development, and translational medicine
Experience with autoimmune disease research or immunology therapeutic pipelines
Ability to communicate complex immunology-based biomarker strategies to cross-functional partners and senior leaders, including research, clinical operations, regulatory, program leadership, and non-immunology scientists
Experience with working on cross-functional teams in the biotech/ pharma industry, showcasing enterprise thinking
Has deep knowledge of the drug development process and a broad perspective of the business
Ability to apply strategic and agile thinking to adapt to the emerging trends in biomarker development/validation
Strong written and verbal communication skills and the ability to effectively communicate with cross-functional teams and present complex science clearly to various stakeholders within the organization
Ability to work collaboratively across business areas and with diverse functional stakeholders to successfully meet project deliverables
Excellent mentor for scientists and employees working on fit-for-purpose assay development
Demonstrated expertise with fit-for-purpose assay development
Preferred
Experience with late-stage program development is highly preferred
Experience with both early and late-stage programs preferred
Benefits
Medical, dental and vision benefits
Generous paid time off (including a week-long company shutdown in the Summer and the Winter)
Educational assistance programs including student loan repayment
A generous commuting subsidy
Matching charitable donations
401(k)
Company
Vertex
Vendor intelligence that combs through your supplier, manufacturer, logistics data to detect where you're leaving money on the table.
2-10 employees
H1B Sponsorship
Vertex has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (27)
2024 (18)
2023 (7)
2022 (13)
2021 (5)
2020 (7)
Funding
Current Stage
Early StageCompany data provided by crunchbase