Broad Institute of MIT and Harvard · 4 weeks ago
Computational Scientist I - Getz Lab
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$88K/yr - $124K/yrThe Broad Institute of MIT and Harvard is a leading laboratory for cancer genome analysis, seeking a Computational Scientist I to join the Getz Lab. The role involves leading computational efforts in collaborative projects focused on genomic mechanisms of therapy resistance in cancer, with opportunities to analyze patient data and develop computational methodologies.
BiotechnologyClinical TrialsLife Science
Responsibilities
Demonstrate initiative in completing projects independently, effectively utilizing available resources and seeking guidance when appropriate
Design and execute data analysis strategies to support multiple data types
Ability to explore and develop tools for analyzing novel data types
Conduct QC analysis of data, identify technical bottlenecks or challenges, and implement solutions to overcome these barriers
Build and run pipelines for analysis of whole-genome sequences (WGS), bulk RNA sequencing, single-cell/single-nucleus RNA sequencing, etc. Such analysis includes discovery of mutations, phylogenetic analysis of tumor evolution during the development of resistance, detection of differentially expressed genes and pathways, detection of expression modules, etc
Develop methods to rank candidate targets based on suitability for therapeutic targeting
Effectively communicate research findings and ideas to diverse audiences within the Getz lab and external clinical collaborators, both verbally and in writing
Ability to critically evaluate new scientific findings within the context of existing dogma, and effectively summarize ideas to make significant contributions to scientific publications, presentations, grants, and patents
Serve as a project lead for the computational aspects of both projects
Mentor and teach junior team members
Qualification
Required
A PhD in Math, Biology, Computer Science, Physics, Statistics, Engineering or a related discipline is required
Experience with computational analysis, algorithm development, statistics and machine learning
Experience analyzing bulk and single cell human genomic and transcript data
Proficiency in at least one modern programming language
Strong verbal and written communication skills
Demonstrated ability to drive projects to completion, evidenced by first-author or significant co-author contributions to accepted, peer-reviewed manuscripts in quality scientific journals
Demonstrated leadership skills as a project lead of computational projects
Experience and ability to meet defined project milestones
Preferred
Postdoctoral experience is a plus
Background in genetics or biology, especially in cancer genomics, is preferred
Previous experience in industry is a plus
Experience in working with and mentoring junior scientists is a plus
Benefits
Medical, dental, vision, life, and disability insurance
401(k) retirement plan
Flexible spending and health savings accounts
At least 13 paid holidays
Winter closure
Paid time off
Parental and family care leave
Employee assistance program
Among other Broad benefits
Company
Broad Institute of MIT and Harvard
The Broad Institute brings together a diverse group of individuals from across its partner institutions — undergraduate and graduate students, postdoctoral fellows, professional scientists, administrative professionals, and academic faculty.
Founded in 2003
1001-5000 employees
H1B Sponsorship
Broad Institute of MIT and Harvard has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (108)
2024 (59)
2023 (73)
2022 (68)
2021 (70)
2020 (93)
Funding
Current Stage
Late StageTotal Funding
$283.25MKey Investors
MacArthur FoundationAlzheimer's Foundation of AmericaMassachusetts Life Sciences Center
2025-11-18Grant· $100M
2020-08-11Grant
2019-09-09Grant· $0.75M
Leadership Team
Dan Shore
Chief Financial Officer
Anne Carpenter
Institute Scientist and Imaging Platform Senior Director
Recent News
Research & Development World
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