Foresite Labs · 2 days ago
Senior Engineer – Signal Processing
San Diego
Full-time
Onsite
Senior Level, Lead/Staff
$260K/yr - $270K/yr
10+ years expForesite Labs is a venture-backed, stealth-stage biotechnology company based in San Diego, focused on developing novel technologies for disease detection and management. They are seeking a Principal Engineer – Signal Processing to lead the creation of a high-throughput bioinformatic signal pipeline, utilizing expertise in signal processing and image processing to enhance data extraction from biological assays.
BiopharmaBiotechnologyHealth CareMedical
Responsibilities
Architect a data processing pipeline that transforms biological signals into discrete data sources for downstream processing
Develop novel algorithms and implement proven algorithms in novel ways to optimize throughput and quality of biological detection systems
Define metrics and diagnostics for the hardware and chemistry teams that allow them to optimize workflow and instrumentation to achieve the highest possible data quality
Define metrics and diagnostics for the bioinformatics team that allow them to optimize performance of downstream assays and applications
Create a modeling and analysis framework to predict future performance and identify key parameters limiting potential data quality. Work with chemistry and hardware teams to prioritize experiments that will guide the system to its theoretical limits
Contribute to the design of future hardware and assays that reach beyond current capabilities to deliver truly groundbreaking results
Qualification
Required
MS or PhD in Electrical Engineering, Computer Science, Physics, Bioinformatics, or related field
MS and 13+ years or PhD and 10+ years of experience in digital or analog signal processing, image analysis, communications, physical layer algorithm development or comparable field
Deep understanding of signal processing, digital communication, and optimal system design
Proficiency in Python, MATLAB, C++ or similar language and high performance computing frameworks
Preferred
Familiarity with machine learning techniques for image processing, channel optimization, or related areas
Experience with GPU-accelerated computation (CUDA, RAPIDS, etc.)
Experience in cross-functional collaboration with engineering, chemistry and biochemistry teams
Record of innovation through publications, patents or open-source contributions
Benefits
Competitive compensation and equity package
Comprehensive benefits
Flexibility to support work-life integration
Company
Foresite Labs
Foresite Labs is a biotechnology company. It is a sub-organization of Foresite Capital.
11-50 employees
H1B Sponsorship
Foresite Labs has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2022 (1)
Funding
Current Stage
Early StageLeadership Team
Alex Blocker
CTO and Chief Data Scientist
Uplaksh Kumar
COO Foresite Labs and Venture Partner Foresite Capital
Recent News
Crunchbase News
2026-01-02
Silicon Republic
2025-11-19
Crunchbase News
2025-11-17
Company data provided by crunchbase