Guardant Health · 13 hours ago
Sr Manager/Associate Director, Accounts Payable (AP) Operations
Palo Alto, CA
Full-time
Hybrid
Senior Level, Lead/Staff, Director/Executive
$164K/yr - $225K/yr
12+ years expGuardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. They are seeking a Sr Mgr/Associate Director, Accounts Payable Operations to lead the Accounts Payable and Travel & Expense functions, ensuring accuracy, compliance, and scalability across operations.
BiotechnologyHealth CareHealth DiagnosticsOncologyTherapeutics
Responsibilities
Own enterprise-wide AP and T&E operations, ensuring accuracy, timeliness, compliance, and scalability across domestic and international activities
Define and execute a multi-year operational roadmap for AP and T&E aligned to the Finance long-range plan
Serve as the senior escalation point for complex AP and T&E issues, balancing risk management with business enablement
Establish and monitor service levels, KPIs, and operational dashboards to drive performance and continuous improvement
Lead, develop, and scale a multi-layered, globally distributed organization, including US and offshore teams
Build management depth and succession capability within AP and T&E functions
Drive consistent performance management, talent development, and engagement across teams
Promote a culture of accountability, ownership, and continuous improvement
Own end-to-end AP and T&E processes, including invoice processing, expense reporting, corporate cards, disbursements, accruals, and compliance reporting
Partner with Finance Systems and IT to lead automation, integration, and optimization initiatives related to AP and T&E platforms (e.g., ERP, OCR, Concur)
Identify and execute opportunities to reduce manual effort, improve cycle times, strengthen controls, and enhance employee and supplier experience
Ensure processes are well-documented, standardized where appropriate, and designed to scale
Partner closely with Procurement and Supply Chain to improve upstream data quality, purchasing compliance, and invoice match rates
Collaborate on initiatives that drive operational efficiencies, reduce exceptions, and improve vendor experience
Act as a finance advisor to Procurement on AP-related impacts of policy, system, and process changes
Maintain strong partnerships with Legal, HR, IT, Tax, Compliance, and Accounting leadership
Maintain strong internal controls across AP and T&E operations in accordance with GAAP, SOX, and company policies
Oversee regulated and high-risk areas, including physician spend tracking (Stark Law), corporate card governance, vendor master controls, and disbursement integrity
Lead AP and T&E-related audit activities and support internal and external audit requirements
Oversee statutory and compliance reporting related to AP, including 1099 and similar filings
Own AP and T&E components of the monthly, quarterly, and annual close, including accruals, reconciliations, journal entries, and variance analysis
Provide leadership with actionable insights on trends, risks, capacity constraints, and improvement opportunities
Develop and maintain operational metrics aligned to finance and enterprise objectives
Qualification
Required
Bachelor's degree in Accounting, Finance, Business, or a related field required; advanced degree and/or CPA preferred
12+ years of progressive accounting or finance operations experience with deep Accounts Payable and Travel & Expense leadership exposure
7+ years of people management experience, including leading managers and globally distributed or offshore teams
Strong experience in a public company environment with a solid understanding of SOX controls, audit requirements, and regulatory compliance
Extensive experience with large ERP environments (Oracle Fusion preferred) and expense management platforms (Concur required)
Demonstrated success leading automation initiatives, systems implementations, and operational scaling efforts
Strong understanding of domestic and international AP and T&E operations, including compliance, accruals, and close processes
Proven ability to lead complex operations while balancing execution, risk management, and continuous improvement
Excellent communication and influencing skills with the ability to partner effectively across Finance, Compliance, Procurement, IT, and business stakeholders
Strong analytical and problem-solving skills with sound judgment and a solutions-oriented mindset
Ability to operate independently, manage ambiguity, and drive results in a fast-paced, scaling environment
Preferred
advanced degree and/or CPA preferred
Oracle Fusion preferred
Company
Guardant Health
Guardant Health is a precision oncology company that uses blood tests, data sets, and analytics to provide treatment to cancer patients.
1001-5000 employees
H1B Sponsorship
Guardant Health has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (38)
2024 (50)
2023 (40)
2022 (72)
2021 (57)
2020 (29)
Funding
Current Stage
Public CompanyTotal Funding
$2.53BKey Investors
Baillie GiffordSoftBank Vision FundOrbiMed
2025-11-05Post Ipo Equity· $284.4M
2025-11-05Post Ipo Debt· $350M
2023-12-21Post Ipo Equity· $90.7M
Leadership Team
AmirAli Talasaz
Co-founder and Co-Chief Executive Officer
Helmy Eltoukhy
Chairman and Co-Chief Executive Officer
Recent News
2026-01-23
Company data provided by crunchbase