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Nucleo (YC F25) · 23 hours ago

Chief of Staff to CEO

San Francisco Bay Area

Full-time

Onsite

Director/Executive

$60K/yr - $120K/yr

Nucleo is building the first agentic platform for oncology, focusing on automating critical steps in the oncology workflow. The Chief of Staff to the CEO will work closely with the CEO to manage business operations, support fundraising efforts, and maintain relationships with hospital customers and partners.

AnalyticsArtificial Intelligence (AI)Information TechnologyMachine Learning

Responsibilities

Partner closely (on a daily basis) with the CEO on all aspects of running the business

Support the CEO in prioritization, communications, and time allocation to ensure focus on the most critical initiatives

Run weekly exec cadences, project trackers, and help prep internal and external communications

Support go-to-market execution: sales ops, outbound campaigns, deal support

Manage and maintain relationships with hospital customers and partners

Support fundraising: investor pipeline, updates, and diligence prep

Keep visibility on company finances: expenses, vendors, basic accounting

Support regulatory execution (FDA / CE): timelines, documentation, coordination

Qualification

Business scalingProject managementSales operationsInvestor relationsHealthcare experienceTechnical backgroundExecution velocityWork ethic

Required

Proven track record of building/scaling a business/project

You are based in SF or willing to relocate within this year (we can support O-1)

You're willing to work in person and travel when needed

Proven ability to manage multiple priorities in a fast-paced, dynamic environment

Instinct for early-stage scrappiness & hustle

Strong work ethic & execution velocity

Preferred

Experience with hospitals, healthcare procurement, or medical sales

Background in, or passion for, SaaS, AI, or technology companies

Medical training (MD, med student, or formal education in medicine / biomedical sciences)

Benefits

0.50% - 1.50% equity

Company

Nucleo (YC F25)

We help oncologists and radiologists by automating medical imaging processing with machine learning.

Founded in 2025

San Francisco, California, USA

2-10 employees

https://nucleoresearch.com

Funding

Current Stage

Early Stage

Total Funding

$0.5M

Key Investors

Y Combinator

2025-12-03Pre Seed· $0.5M

Leadership Team

Angelica Iacovelli

CEO

Luca Pegolotti

CTO

Company data provided by crunchbase