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Nucleo (YC F25) · 21 hours ago

Chief of Staff to CEO

United States

Full-time

Remote

New Grad, Entry Level

$60K/yr - $120K/yr

Nucleo is a YC-backed deep-tech company, and they are seeking a Chief of Staff to work directly with the CEO in building the company. The role involves supporting the CEO in prioritization, managing communications, and overseeing various operational tasks to ensure the company's growth and success.

AnalyticsArtificial Intelligence (AI)Information TechnologyMachine Learning

H1B Sponsored

Responsibilities

Partner closely (on a daily basis) with the CEO on all aspects of running the business

Support the CEO in prioritization, communications, and time allocation to ensure focus on the most critical initiatives

Run weekly exec cadences, project trackers, and help prep internal and external communications

Support go-to-market execution: sales ops, outbound campaigns, deal support

Manage and maintain relationships with hospital customers and partners

Support fundraising: investor pipeline, updates, and diligence prep

Keep visibility on company finances: expenses, vendors, basic accounting

Support regulatory execution (FDA / CE): timelines, documentation, coordination

Qualification

Problem-SolvingWork EthicExecution VelocityManage PrioritiesScrappinessHustleHealthcare procurement experienceMedical sales experienceSaaS backgroundAI knowledgeTechnology companies experienceMedical trainingBiomedical sciences education

Required

Proven track record of building/scaling a business/project. We don't care whether your background is business, technical, or something else

You are based in SF or willing to relocate within this year (we can support O-1)

You're willing to work in person and travel when needed

Proven ability to manage multiple priorities in a fast-paced, dynamic environment. Instinct for early-stage scrappiness & hustle

Strong work ethic & execution velocity

Preferred

Experience with hospitals, healthcare procurement, or medical sales

Background in, or passion for, SaaS, AI, or technology companies

Medical training (MD, med student, or formal education in medicine / biomedical sciences)

Benefits

0.50% - 1.50% equity

Company

Nucleo (YC F25)

We help oncologists and radiologists by automating medical imaging processing with machine learning.

Founded in 2025

San Francisco, California, USA

2-10 employees

https://nucleoresearch.com

Funding

Current Stage

Early Stage

Total Funding

$0.5M

Key Investors

Y Combinator

2025-12-03Pre Seed· $0.5M

Leadership Team

Angelica Iacovelli

CEO

Luca Pegolotti

CTO

Company data provided by crunchbase