Chief of Staff to CEO jobs in United States
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Nucleo (YC F25) · 22 hours ago

Chief of Staff to CEO

positionSan Francisco, CA, US
timeFull-time
remoteHybrid
seniorityNew Grad, Entry Level
money$60K/yr - $120K/yr

Nucleo is a YC-backed deep-tech company, and they are seeking a Chief of Staff to work directly with the CEO in building the company. The role involves supporting the CEO in prioritization, managing communications, and overseeing various operational tasks to ensure the company's growth and success.

AnalyticsArtificial Intelligence (AI)Information TechnologyMachine Learning
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Responsibilities

Partner closely (on a daily basis) with the CEO on all aspects of running the business
Support the CEO in prioritization, communications, and time allocation to ensure focus on the most critical initiatives
Run weekly exec cadences, project trackers, and help prep internal and external communications
Support go-to-market execution: sales ops, outbound campaigns, deal support
Manage and maintain relationships with hospital customers and partners
Support fundraising: investor pipeline, updates, and diligence prep
Keep visibility on company finances: expenses, vendors, basic accounting
Support regulatory execution (FDA / CE): timelines, documentation, coordination

Qualification

Problem-SolvingWork EthicExecution VelocityManage PrioritiesScrappinessHustleHealthcare procurement experienceMedical sales experienceSaaS backgroundAI knowledgeTechnology companies experienceMedical trainingBiomedical sciences education

Required

Proven track record of building/scaling a business/project. We don't care whether your background is business, technical, or something else
You are based in SF or willing to relocate within this year (we can support O-1)
You're willing to work in person and travel when needed
Proven ability to manage multiple priorities in a fast-paced, dynamic environment. Instinct for early-stage scrappiness & hustle
Strong work ethic & execution velocity

Preferred

Experience with hospitals, healthcare procurement, or medical sales
Background in, or passion for, SaaS, AI, or technology companies
Medical training (MD, med student, or formal education in medicine / biomedical sciences)

Benefits

0.50% - 1.50% equity

Company

Nucleo (YC F25)

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We help oncologists and radiologists by automating medical imaging processing with machine learning.
dateFounded in 2025
location
San Francisco, California, USA
people-size2-10 employees
web-link
https://nucleoresearch.com

Funding

Current Stage
Early Stage
Total Funding
$0.5M
Key Investors
Y Combinator
2025-12-03Pre Seed· $0.5M

Leadership Team

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Angelica Iacovelli
CEO
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Luca Pegolotti
CTO
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Company data provided by crunchbase