Inside Higher Ed · 18 hours ago
Senior Research Scientist, Georgia Cancer Center
Augusta, GA
Full-time
Onsite
Senior Level, Lead/Staff
10+ years expAugusta University is seeking a highly motivated faculty member for the Georgia Cancer Center as a Senior Research Scientist with a focus on CAR-T Cell Therapy discovery research. The role involves designing, developing, and optimizing CAR-T cell candidates while collaborating with cross-functional teams to advance these candidates to clinical application.
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Responsibilities
Independently plan, execute, analyze, and report on experiments to support the preclinical development of novel T cell therapy products
Genome editing and culturing human pluripotent stem cells in various conditions
Perform in vitro cell-based functional assays (cytotoxicity, cytokine, proliferation, etc.) for CAR T cell therapeutic candidate selection
Design, execute, and analyze flow cytometry experiments for CAR T cell product characterization
Support engineered T cell production activities (e.x. gene editing, T cell culture, cryopreservation, cell thawing)
Culture both engineered primary T cell and suspension/adherent cell lines
Support IND-enabling preclinical studies
Coordinate tasks across multiple projects and teams, demonstrating prioritization and planning
Qualification
Required
PhD or equivalent in Cell or Molecular Biology/Biological Sciences with 10 or more years research experience
Extensive hands-on experience with Molecular Biology (as PCR, qRT-PCR, ddPCR, DNA/RNA and protein preparation), Cloning, mammalian cell culture and transfection
Experience with multi-color flow cytometry, panel design, and data analysis
Willingness to accept responsibilities outside of initial job description
Preferred
Experience with human CAR T cell engineering
Experience using viral (lentiviral, retroviral or AAV) and/or non-viral gene delivery methods (e.g., CRISPR mediated knock-in or targeted genome integration)
Experience with immunological assays, such as cytokine/chemokine analysis (e.x. ELISA or Luminex), cytotoxicity and in vitro cell based assays live cell analysis
Proficiency in using data analysis tools such as FlowJo and GraphPad Prism
Understanding of US FDA cGMP and international regulatory requirements is welcomed
Benefits
Comprehensive benefits include medical, dental, vision, 13 paid holidays, vacation leave, sick leave, generous retirement plans, tuition waiver, wellness options, and much more!
Full-time employees who have been employed with us successfully for more than 6 months can be considered for the Tuition Assistance Program.
Company
Inside Higher Ed
Inside Higher Ed is the online source for news, opinion, and jobs related to higher education.
51-200 employees
Funding
Current Stage
Growth StageTotal Funding
unknown2022-01-10Acquired
2006-08-31Series Unknown
Leadership Team
Stephanie Shweiki
Director, Foundation Partnerships
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