Amgen · 23 hours ago
Process Development Sr Scientist
Thousand Oaks, CA
Full-time
Onsite
Senior Level
5+ years expAmgen is a leading biotechnology company dedicated to serving patients with serious illnesses. The Process Development Sr Scientist role involves supporting early formulation development and physicochemical characterization to advance preclinical and clinical development programs, contributing to regulatory filings and intellectual property.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Evaluation of drug candidate stability, structural elucidation, and identification of degradation pathways
Synthetics molecule assessment (developability assessment) and preclinical formulation support
Supporting lead optimization and form selection to meet the target product profile
Application of in silico and in vitro models to support molecule and biopharmaceutical assessments and identify development strategies
Coordinate with team members and external partners to meet defined tasks and project milestones
Support the project team lead to author technical reports and analytical Chemistry, Manufacturing and Controls (CMC) sections in regulatory documents
Apply continuous improvement practices to enhance overall laboratory efficiency
Qualification
Required
Bachelor's degree and 5 years of Scientific experience OR
Master's degree and 3 years of Scientific experience OR
Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable]
Preferred
Doctorate Degree (PhD OR PharmD) with 2+ years of post-PhD experience in Pharmaceutics, Pharmacy, Chemistry or related field preferred
Experience in synthetic, mechanistic, or physical organic chemistry, and structural elucidation is informed by knowledge of organic chemistry
Strong understanding in Mass Spectrometry or Liquid Chromatography Mass Spectrometry (LCMS)
Experience in preformulation techniques including HPLC analysis, physicochemical evaluation (solubility, stability, pKa and LogP determination, etc.) and solid-state characterization (DSC, TGA, XRPD, microscopy, moisture sorption, particle characterization, etc.) is beneficial
Experience in chemical kinetics, pharmacokinetics or biopharmaceutical modeling is beneficial
Ability to take initiative, work independently, and be flexible in responsibilities
Experience in liquid dosage forms (e.g. drug-in-bottle, parenteral, inhalation, topical) for synthetics
An ability to integrate automation solutions and data science approaches to enhance laboratory workflows
Proficiency with instrumentation platforms and client-server data management systems
Experience applying statistical analysis and data visualization tools
Problem solver with a proactive demeanor and ability to collaborate and work in a cross functional/multidisciplinary environment
Excellent written, verbal, and presentation skills – ability to distill, craft and present key messages relative to diverse audience requirements
Benefits
A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans
Flexible work models, including remote and hybrid work arrangements, where possible
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
2026-01-24
2026-01-22
Company data provided by crunchbase