San Diego Supercomputer Center · 20 hours ago
Staff Research Associate III - 138222
San Diego, CA
Full-time
Onsite
Senior Level, Lead/Staff
$70K/yr - $112K/yr
4+ years expThe San Diego Supercomputer Center is part of UC San Diego, which focuses on achieving high standards in patient care, research, and education. The role involves performing experiments related to neuronal cytoskeleton understanding and developing CRISPR-based therapeutics for neurodegenerative diseases, while leading various lab responsibilities.
Big DataDatabaseInformation Technology
Responsibilities
Perform experiments and interpret results related to a wide range of basic and translational experiments in the lab, including sophisticated experiments related to a deeper understanding of the neuronal cytoskeleton and its role in human diseases
Collaborate with the PI and other lab members in the development of CRISPR-based therapeutics for Parkinson’s and Alzheimer’s disease
Lead and take complete charge of all intellectual and technical aspects of work, including design/execution of the research, as well as interpretation of the result, in addition to advancement of translational tools like CRISPR-based therapeutics
Perform routine cell/molecular assays – cell culture, PCR, cell-based assays, protein blotting, flow cytometry etc
Perform non-standard procedures including sample preparation and optimization, quality control, and data analysis
Oversee lab members’ use of shared instrumentation, including troubleshooting problems and performing limited maintenance
Oversee undergraduate researchers and contribution to planning and execution of experiments
Help with data processing and presentation and statistical analysis as needed
Contribute to lab administration, compliance, and maintenance
Qualification
Required
Knowledge in biomedical or a related science generally acquired through a Bachelor's degree, or an equivalent combination of education and experience. Preferably four years of research experience
Knowledge of molecular biology techniques and genetics and experience in extracting DNA/RNA, PCR, and qPCR
Experience in protein chemistry/purification, gel electrophoresis and transfers, various gel and membrane stains, western blots, and densitometry and analysis on resulting data
Experience and knowledge of bio, chemical, and radiation safety techniques and practices. Demonstrated ability to follow established Safety and Biohazardous Material Guidelines and implement measures to ensure compliance and maintain associated records
Experience writing scientific manuscripts for publication in scientific journals and other scholarly and research-oriented publications
Experience using computer software for the analysis and visualization of experimental data. Demonstrated ability to learn new software and/or computer hardware, or expand existing knowledge, to meet the needs of research
Excellent oral and written communication skills with the additional ability to communicate information effectively in person, on the telephone or via email to a diverse population of researchers and lay people
Sterile techniques and ability to recognize and identify contaminants and devise methods to eliminate them
Strong organizational skills with the ability to work independently
Experience to independently identify new areas of research, develop hypothesis or identify questions, formulate new models, design and carry out necessary experiments to test these models, analyze data, write-up results for publications
Experience and knowledge to develop new research and experimental techniques to meet research objectives
Experience and demonstrated ability to initiate and maintain multiple different eukaryotic cell lines including freezing, thawing, storage, and plating cells in preparation for experiments. Experience with sterile techniques, trouble shooting of contamination problems, and care of incubators and liquid nitrogen freezers
Experience with gel/blot imaging and microscopic imaging techniques for both fluorescence and bright field applications and with digital histology image software assisted image processing and analysis. Experience with advanced imaging equipment such as photoactivation/conversion using DMD devices, TIRF and superresolution (STED) microscopy
Company
San Diego Supercomputer Center
SDSC enables science and engineering discoveries through advances in computational science and data-intensive, high-performance computing.
201-500 employees
Funding
Current Stage
Growth StageTotal Funding
unknownKey Investors
National Science Foundation
2024-12-05Grant
Leadership Team
Ilkay Altintas
Division Director, Cyberinfrastructure and Convergence Research and Education
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