Merck · 14 hours ago
Associate Scientist, Post Doctoral Fellow, Neuroimmunology
Lansdale, PA
Full-time
Onsite
New Grad, Entry LevelMerck is a large pharmaceutical company committed to breakthrough innovation in research and discovery. They are seeking an energetic and innovative postdoctoral fellow with expertise in immunology, cell biology, or neuroscience to join their Neuroscience team, focusing on projects that bridge Neuroscience and Infectious Disease & Vaccines.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Design and execute mechanistic studies and develop relevant models to test hypotheses
Work closely with mentors and a multidisciplinary team to shape research plans, generate robust data, and produce novel, field-advancing insights in neuroimmunology
Launch and lead independent projects that investigate how adaptive immunity changes with aging and how these changes influence neurodegenerative disease
Establish and optimize models of innate and adaptive immune modulation in pre-clinical species
Develop immunological assays to characterize innate and antigen-specific humoral and cellular immune responses
Perform neurodegenerative pathology analysis in animal models of disease using immunohistochemistry, western blot, Meso scale discovery assay et.al
Perform single cell assays including high-parameter flow cytometry and single cell omics profiling (e.g. single cell RNAseq and immune repertoire profiling)
Data interpretation, manuscript and patent preparation, publication, and presentation
Qualification
Required
Ph.D. completed within 6 months of hire in Immunology, Cell biology, Neuroscience or related field
Expertise in in vivo immunological response studies
Hands-on experience working with pre-clinical animal models and manipulating samples derived from these models
Hands-on experience and solid knowledge in aseptic techniques in tissue culture
Hands-on experience and solid knowledge in molecular biology and cell biology
Hands-on experience with in vitro assay development and troubleshooting
Experience in immunological assays (e.g. ELISA, ELISPOT, high-parameter flow cytometry, cell sorting, in vitro restimulation assays)
Strong publication record and ability to design and execute experiments and interpret data
Excellent communication and collaboration skills
Assay, Assay Development, Biochemical Assays, Blotting Techniques, Cell-Based Assays, Cell Biology, Cell Culture Techniques, Immunoassays, Immunochemistry, Immunofluorescence Microscopy, Immunology, In Vitro Assays, In Vivo Mouse Models, Molecular Biology, Neuroanatomy, Neurotrophins, Scientific Writing, Tissue Cultures
Preferred
Experience in biochemistry/molecular biology assays (immunohistochemistry, western blot, Meso Scale Discovery assay et.al.)
Familiarity or experience with single-cell omics assays and data analysis, in vitro restimulation assays
Familiarity or experience with Alzheimer's disease animal models
Familiarity or experience with vaccine platforms
Company
Merck
Merck is a biopharmaceutical company that offers medicines and vaccines for various diseases.
Founded in 1891
10001+ employees
Funding
Current Stage
Public CompanyTotal Funding
$5.59MKey Investors
Private Capital AdvisorsGavi, the Vaccine Alliance
2018-11-25Post Ipo Equity· $0.59M
2016-01-21Series Unknown· $5M
1980-12-19IPO
Leadership Team
Betty Larson
Executive Vice President and Chief Human Resources Officer
Dean Li
Executive Vice President and President, Merck Research Laboratories
Recent News
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