Payroll Tax Specialist – US Payroll (People Services) jobs in United States
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Alexion Pharmaceuticals, Inc. · 13 hours ago

Payroll Tax Specialist – US Payroll (People Services)

AstraZeneca is a company that turns ideas into life‑changing medicines, and they are seeking a Payroll Tax Specialist to ensure accurate, timely, and compliant payroll outcomes for approximately 18,000 employees across multiple legal entities. The role involves applying practical experience in US payroll taxes to support operations, controls, reconciliations, and continuous improvement.

BiotechnologyHealth CareMedicalTherapeutics
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Comp. & Benefits
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H1B Sponsor Likelynote

Responsibilities

Translate business requests into mass‑upload templates, submit inputs to our payroll provider, perform pre‑/post‑pay audits, and validate gross‑to‑net with a focus on tax accuracy
Apply federal, state, and local tax rules (FIT, SIT, SUI/SUTA, SDI, local taxes), supplemental wage taxation, reciprocity, and resident/non‑resident considerations
Support new state/local tax setups, maintain accounts and rates, manage authorizations, and work with agencies to resolve notices and discrepancies
Review and validate system updates affecting taxability and withholding (e.g., work vs. resident state, locality setup, tax elections, and taxability matrices)
Perform payroll and tax tie‑outs, investigate variances, and ensure accurate taxation of earnings and pre‑/post‑tax deductions
Research and resolve employee and agency tax inquiries, overpayments/repayments, garnishments, and edge cases; monitor regulatory changes and recommend adjustments
Validate taxable wage drivers from time data (overtime, differentials, shift premiums), identify variances, and ensure correct taxation
Coordinate with the payroll provider on issues, SLAs, and defect remediation; support audits, controls, and process improvements
Provide clear guidance to managers and employees on tax elections and impacts; mentor colleagues on tax fundamentals and best practices

Qualification

US payroll tax experienceMicrosoft ExcelHCM/payroll system experienceFPC certificationCPP certificationAnalytical skillsCuriosityClear communicationTeam collaboration

Required

High School Diploma required
Practical, hands‑on experience with US payroll taxes in a multi‑state environment (in‑house or via a payroll provider)
High proficiency with Microsoft Excel (pivot tables, lookups, reconciliations)

Preferred

Bachelor's Degree
Experience with a major HCM/payroll system (Workday or similar)
FPC or CPP preferred (we support learning paths toward certification)

Company

Alexion Pharmaceuticals, Inc.

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Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community.

H1B Sponsorship

Alexion Pharmaceuticals, Inc. has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (49)
2024 (57)
2023 (51)
2022 (29)
2021 (27)
2020 (17)

Funding

Current Stage
Public Company
Total Funding
$5.8M
2020-12-12Acquired
1999-02-12Post Ipo Equity· $5.8M
1996-02-29IPO

Leadership Team

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Frederic Chereau
SVP, Strategy and Business Development
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Imran Shakur
Director, IRT and Technology Lead
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Company data provided by crunchbase