Alnylam Pharmaceuticals · 23 hours ago
Associate Director, Clinical Pharmacology
Cambridge, MA
Full-time
Hybrid
Lead/Staff, Director/Executive
$176K/yr - $238K/yr
5+ years expAlnylam Pharmaceuticals is a leader in RNAi therapeutics, aiming to transform the lives of individuals with rare and common diseases. They are seeking an Associate Director in Clinical Pharmacology to develop and execute pharmacometric strategies and models for clinical studies, while managing multiple development projects and collaborating with cross-functional teams.
BiotechnologyHealth CareMedicalPharmaceuticalTherapeutics
Responsibilities
As the M&S project lead on one or more cross-functional development teams, develop and execute M&S strategies and plans fully integrated with the overall preclinical and clinical plans
By using state of the art M&S methodologies strongly contribute to decision making at critical milestones based on quantitative principles in close collaboration with DMPK, Stat, Clin Pharm, Medical Sciences, Research, and other quantitative disciplines
Perform population PK, PK/PD analyses, clinical trial simulations and other model-based analyses when appropriate
Strengthen and build internal M&S capability on a continuous basis by attending trainings, evaluating and introducing new M&S tools and computing platform as appropriate
Prepare population PK/PD reports and corresponding regulatory submission documents
Qualification
Required
A PhD, degree or equivalent in quantitative sciences, background in engineering, or clinical pharmacology is desired
5+ years pharmaceutical industrial and/or postdoctoral experiences in the related disciplines of clinical pharmacology, and PKPD
Excellent hands-on knowledge in R and/or SAS, NONMEM
Well versed at plotting complex data to identify trends important for drug development
Track record of publishing M&S work
Excellent written and verbal communication skills
Benefits
Medical, dental, and vision coverage
Life and disability insurance
A lifestyle reimbursement program
Flexible spending and health savings accounts
A 401(k) with a generous company match
Paid time off
Wellness days
Holidays
Two company-wide recharge breaks
Generous family resources and leave
Company
Alnylam Pharmaceuticals
Alnylam Pharmaceuticals is a biopharmaceutical company focused on the discovery, development and commercialization.
1001-5000 employees
H1B Sponsorship
Alnylam Pharmaceuticals has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2022 (18)
2021 (19)
2020 (7)
Funding
Current Stage
Public CompanyTotal Funding
$4.55BKey Investors
Blackstone Life SciencesBlackstone CreditRegeneron
2025-09-09Post Ipo Debt· $661.25M
2022-09-12Post Ipo Debt· $900M
2022-03-04IPO
Leadership Team
Yvonne Greenstreet
Chief Executive Officer
Jeff Poulton
Chief Financial Officer
Recent News
Clinical Trials Arena
2026-01-16
Longevity.Technology
2026-01-14
2026-01-13
Company data provided by crunchbase