Eli Lilly and Company · 7 hours ago
Scientist/Sr. Scientist - Large Molecule Biology
New York, NY
Full-time
Onsite
Senior Level
$71K/yr - $187K/yr
5+ years expEli Lilly and Company is a global healthcare leader headquartered in Indianapolis, Indiana. They are seeking a Scientist/Sr. Scientist in the Large Molecule Biology group to execute experiments supporting research programs, oversee portfolio programs, and develop biologic assays for drug development. The role involves collaboration across teams and presenting findings to internal stakeholders.
BiotechnologyHealth CareMedicalPharmaceutical
Responsibilities
Design and implement studies to identify, evaluate, and advance therapeutic candidates through the drug development pipeline
Demonstrate laboratory expertise with biologic assays aimed at drug development, specifically utilizing monoclonal antibodies (mAb), antibody-drug conjugates (ADC), and CD3 platforms
Manage the maintenance, culture, and passaging of multiple cell lines to support experimental objectives
Perform comprehensive functional assays and high-throughput screenings, including tumor cell signaling, internalization, cytotoxicity, effector function and cytokine release assays, to assess cellular responses
Conduct multi-parameter flow cytometry assays to determine binding interactions and accurately quantify receptor density across diverse cell populations
Conduct candidate evaluation in both in vitro (PK/PD, receptor occupancy, density, cytokine release), and ex vivo assays (tumor isolation, analysis of blood cells)
Develop, validate, and perform bioanalytical assays—including ELISA—to precisely quantify proteins and antibodies relevant to experimental outcomes
Critically assess and monitor experimental procedures performed by third-party collaborators and vendors to ensure compliance with study protocols and quality standards
Work with the project leader and senior leader to design and execute assays for the development of the molecule
Present your work to internal teams and summarize findings in preclinical reports
Communicate results at project team meetings, be involved in the coordination and preparation of presentations
Discuss results with technical as well as non-technical personnel
Work in cross functional environments via extensive collaboration with other parts of the organization
Qualification
Required
Bachelors degree in biological sciences or related scientific field with 5+ years of experience or Master's in biological sciences or related scientific field with 2+ years of experience
Preferred
Experience with mammalian cell culture
Extensive expertise performing in vitro, and ex vivo assays
Strong data analysis skills with attention to detail
Ability to design comprehensive experimental plans and carry out in a timely fashion
Deep expertise in cancer disease states (indications, mutational status, tumor cell drivers)
Demonstrated experience in working collaboratively across various scientific disciplines to meet end goals of business
Excellent communication and interpersonal skills
Demonstrated ability to succeed in a fast-paced environment, working on multiple projects with constantly changing priorities and deadlines
Benefits
Company bonus
Company-sponsored 401(k)
Pension
Vacation benefits
Eligibility for medical, dental, vision and prescription drug benefits
Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
Life insurance and death benefits
Certain time off and leave of absence benefits
Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
Company
Eli Lilly and Company
We're a medicine company turning science into healing to make life better for people around the world.
10001+ employees
H1B Sponsorship
Eli Lilly and Company has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (514)
2024 (236)
2023 (167)
2022 (133)
2021 (57)
2020 (52)
Funding
Current Stage
Public CompanyTotal Funding
$6.5M2024-02-12Post Ipo Debt· $6.5M
1978-01-13IPO
Leadership Team
David Ricks
Chair, CEO
Lucas Montarce
Executive Vice President and Chief Financial Officer
Recent News
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