The University of North Carolina at Chapel Hill · 1 week ago
Post-Doc Research Associate - Sharma Lab
Chapel Hill, NC
Full-time
Onsite
Senior LevelThe University of North Carolina at Chapel Hill is a leading public research institution known for its commitment to innovative teaching and research. The role of Post-Doc Research Associate involves assessing neuroimmune interactions in mucosal immunity, conducting experiments with murine models, and analyzing immune functions.
EducationHigher EducationUniversities
Responsibilities
Conduct experiments using murine models of colitis and colorectal cancer and analyze immune functions using multi-parametric flow cytometry and transcriptional analysis
Conceptualize and execute experiments, analyze data and write manuscripts towards assessing the function of sympathetic neurons in mucosal immunity
Qualification
Required
PhD in Immunology or related fields
Experience with mouse genetics and generating/maintaining conditional knockout models
Competency in in vivo experimental models, particularly colitis and colorectal cancer
Expertise in isolating and purifying specific immune cell populations (IECs, IE-T cells, macrophages) from tissues- including intestinal, spleen and MLN
T cell functional assays including stimulation protocols, cytokine production analysis
ELISA and multiplex cytokine quantification
Tissue explant culture and ex vivo functional assessments
Advanced flow cytometry skills including multi-parameter analysis (up to 15+ color panels), tetramer staining, and intracellular cytokine detection
Western blotting for phospho-proteins and signaling pathway analysis
Proficiency in molecular biology techniques (qRT- PCR, Western blotting, ELISA, multiplex assays)
Preferred
Advanced imaging skills including immunohistochemistry, immunofluorescence, whole-mount tissue imaging, confocal microscopy, and 3D image reconstruction
Ability to design complex multi-factorial experiments integrating genetic, pharmacological, and physiological manipulations
Project management skills to coordinate parallel experimental streams
Experience with host-pathogen interactions, immune regulation, innate and adaptive immune responses
Benefits
Comprehensive medical and vision coverage
Paid leave
Benefits and services that support professional development and a healthy work/life balance
Company
The University of North Carolina at Chapel Hill
Carolina’s vibrant people and programs attest to the University’s long-standing place among leaders in higher education since it was chartered in 1789 and opened its doors for students in 1795 as the nation’s first public university.
Founded in 1919
10001+ employees
H1B Sponsorship
The University of North Carolina at Chapel Hill has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (165)
2024 (143)
2023 (100)
2022 (133)
2021 (83)
2020 (89)
Funding
Current Stage
Late StageTotal Funding
$48.57MKey Investors
SECU FoundationCDA FoundationNorth Carolina Biotechnology Center
2024-07-19Grant· $1M
2024-03-18Grant
2023-02-16Grant· $0.11M
Leadership Team
Judith Cone
Retired Vice Chancellor for Innovation, Entrepreneurship and Innovation as of April 1, 2021
Michael Williams
Network SEcurity Team Lead
Recent News
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2025-09-20
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