Roche · 1 week ago
2026 Summer Intern - Translational Safety (Computational Toxicology)
South San Francisco
Internship
Onsite
Intern
$50/hr - $50/hr
Start in 2026 SummerRoche is a leading biotechnology company, and they are seeking a summer intern for their Computational Toxicology group within the Translational Safety department. The intern will work on expanding the capabilities of LLM-powered AI agents by developing a new module for natural-language access to gene expression and cell-type context resources, supporting toxicologists and pathologists in their research.
BiotechnologyHealth CareHealth DiagnosticsOncologyPharmaceuticalPrecision Medicine
Responsibilities
Enable user-friendly queries that return quantitative tissue- and cell-type expression summaries, with robust filtering over key metadata (e.g., tissue, cell type, annotation, condition)
Develop MCP-based tools and prompt/context patterns that connect the agent to expression datasets and execute the underlying retrieval reliably
Perform practical data harmonization to support consistent cross-dataset interpretation (e.g., feature/metadata standardization; gene set/pathway queries)
Integrate the module into the existing agent experience and standardize outputs for scientific review, including basic visualization (tables/plots)
Develop a lightweight evaluation/testing framework based on representative stakeholder questions, and produce basic training materials and usage examples
Qualification
Required
Must be pursuing a Master's Degree (enrolled student)
Must have attained a Master's Degree
Must be pursuing a PhD (enrolled student)
Computer Science, Bioinformatics, Cheminformatics, Computational Biology, Computational Toxicology, Machine Learning & AI, Data Science or related fields
Strong proficiency in Python for data manipulation, analysis pipelines, and rapid prototyping
Hands-on experience working with LLMs, including prompt/context engineering and tool-using agents
Experience working with gene expression datasets and associated metadata (e.g., tissue, cell type, annotations); familiarity with common bioinformatics data structures and workflows
Ability to build reproducible workflows (version control, documentation, unit testing, etc.)
Strong communication, collaboration, and interpersonal skills
Preferred
Excellent communication, collaboration, and interpersonal skills
Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion
Experience building or integrating MCP tools and working with agentic development environments/clients (e.g., Cursor, Claude Code, or similar)
Familiarity with single-cell expression concepts and tooling (e.g., Scanpy/AnnData, Seurat, cell-type annotation)
Experience using GTEx and other tissue- and cell-type reference atlases; experience working with APIs, lightweight services, or query layers over scientific datasets
Strong problem-solving mindset and interest in working at the intersection of life sciences and AI to solve real-world drug safety challenges
Benefits
Paid holiday time off benefits
Company
Roche
Roche is a pharmaceutical and diagnostics company that offers medicines and diagnostic tests for various medical conditions and diseases.
Founded in 1896
10001+ employees
H1B Sponsorship
Roche has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (12)
2024 (9)
2023 (6)
2022 (2)
2021 (2)
Funding
Current Stage
Public CompanyTotal Funding
$7.79BKey Investors
SoftBankSCALE AINovartis
2021-08-04Post Ipo Equity· $5B
2020-12-07IPO
2020-05-06Post Ipo Equity· $0.5M
Leadership Team
Alan Hippe
Member of the Executive Board - Group CFO
Christine Bakan
Global Head and Group Vice President, Computational Science and Informatics R&D
Recent News
2026-01-25
2026-01-23
2026-01-22
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