Associate Scientist Antibody Discovery jobs in United States
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St. Jude Children's Research Hospital · 1 day ago

Associate Scientist Antibody Discovery

St. Jude Children's Research Hospital is dedicated to ensuring that no child will die at the dawn of life. They are seeking an Associate Scientist in Antibody Discovery to develop and implement strategies for improving molecular biology processes, ensuring high-quality protein and biologics for discovery purposes.

BiotechnologyCharityHealth CareHealth DiagnosticsHospitalMedicalNon Profit
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Growth Opportunities
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H1B Sponsor Likelynote

Responsibilities

Work closely with mAb discovery platforms to support molecular biology workflows; design and execute construct generation for antibody expression
Perform DNA preparations to generate high-quality plasmid material for mammalian cell transfection
Develop and optimize high-throughput mammalian cell-based production platforms for recombinant antibodies, antigens, and other biologics
Establish scalable transient and stable expression workflows in CHO, HEK293, and other mammalian expression systems
Purification using AKTA chromatography systems
High-Performance Liquid Chromatography Size Exclusion Chromatography (HPLC-SEC) analysis of purified proteins
Molecular assessment of early-stage development candidates (polyreactivity ELISA, CE-SDS, SEC-MALS, DSF)
Maintain accurate and timely ELN data

Qualification

Protein engineeringMolecular biology workflowsHigh-throughput productionAKTA chromatographyAntibody characterizationBioinformatics softwareResearch experienceLaboratory trainingTeam collaboration

Required

Bachelor's degree in a relevant scientific area
7 + years of research experience is required
5 + years of research experience is required with a Master's degree
2 + years of research experience is required with a PHD
Experience leading and supporting research experiments

Preferred

Experience with modern AKTA chromatography systems (FPLC) for affinity capture and SEC chromatography
Experience with high-throughput automated protein purification systems (e.g. Kingfisher)
Experience with antibody-related bioinformatic/software packages
Expertise in high-throughput molecular biology approaches for construct generation
Experience with mAb characterization techniques (FACS, BLI, epitope binning)
Some experience leading lab and scientific project coordination, maintenance, and other research support activities
Experience in guiding and training other laboratory personnel
Proven performance in earlier role/comparable role

Company

St. Jude Children's Research Hospital

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H1B Sponsorship

St. Jude Children's Research Hospital has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (370)
2024 (316)
2023 (309)
2022 (255)
2021 (251)
2020 (201)

Funding

Current Stage
Late Stage
Total Funding
$62.4M
Key Investors
Kia MotorsKBR Charity Golf TournamentHyundai Hope On Wheels
2025-05-12Grant· $1.5M
2024-10-28Grant
2024-08-28Grant· $0.4M

Leadership Team

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Judy A. Habib
Chair, Board of Directors
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Company data provided by crunchbase