Flagship Pioneering · 7 hours ago
Senior Scientist, Therapeutic Discovery
Cambridge, MA
Full-time
Onsite
Mid, Senior Level
$126K/yr - $182K/yr
5+ years expFlagship Pioneering is a privately held biotechnology company engineering nature to build next generation peptide therapeutics. The role involves leading the development of a therapeutic discovery platform, integrating AI/ML and advanced analytical techniques to drive data-informed decisions in drug design.
FinanceFinancial ServicesVenture Capital
Responsibilities
Prioritize biosynthetic pathways computationally; translate into build hypotheses
Execute wet-lab workflows to build and interrogate genetic designs and run screening/selection assays tied to therapeutic-relevant readouts
Build reproducible pipelines to integrate with multi-modal data structures that drive therapeutic candidate prioritization strategies
Partner cross-functionally with analytical chemistry and AI-enabled discovery workflows to deliver platform proof of concept data
Qualification
Required
PhD in a relevant field; strong record of independent technical ownership, with 5+ years of experience
True hybrid skillset: Python/R (stats, reproducibility, version control) + strong bench execution (molecular biology/expression, enzyme assays, library-oriented experimentation)
Demonstrated expertise in enzyme discovery and characterization; ML/representation or structure-informed approaches a plus
Working knowledge of LC‑MS(/MS) in molecular discovery and proficiency with sequencing-enabled measurements (e.g., NGS-based readouts)
Experience designing/running screening or selection workflows and translating outcomes into follow-on experimental plans; strong cross-audience communication
Preferred
Comfort in ambiguity; can move between strategy and execution
Creative and rigorous in experimental design, documentation, and data interpretation
Collaborative communicator; gives/receives feedback effectively
Grit and agility in fast-moving environments
Benefits
Healthcare coverage
Annual incentive program
Retirement benefits
A broad range of other benefits
Company
Flagship Pioneering
Flagship Pioneering is a venture capital firm that invests in life sciences and healthcare companies.
501-1000 employees
H1B Sponsorship
Flagship Pioneering has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (8)
2024 (4)
2023 (4)
2022 (4)
2021 (1)
Funding
Current Stage
Late StageLeadership Team
Noubar Afeyan
Founder and CEO
Chuck Carelli
Chief Financial Officer
Recent News
2026-01-16
2026-01-16
Company data provided by crunchbase