ImmunEdge · 1 day ago
Associate Scientist, In Vivo Pharmacology
Redwood City, CA
Full-time
Onsite
Mid, Senior Level
$119K/yr - $128K/yr
6+ years expImmunEdge is a biopharmaceutical company focused on developing innovative therapeutics for serious diseases. They are seeking an Associate Scientist in In Vivo Pharmacology to design and execute in vivo studies, contributing to oncology and immunology programs.
Biotechnology
Responsibilities
Design, execute, and interpret in vivo efficacy, PK/PD, and mechanistic studies in relevant oncology and immunology models
Effectively contribute to safety/toxicology studies and assessments in murine models
Perform necropsies and tissue collection, process tissue and perform flow-cytometry based staining and sample acquisition
Collaborate with discovery, translational, and biomarker teams to leverage study-derived samples and develop ex vivo mechanistic assays (MSD, bulk RNA-seq, scRNA-seq) that inform disease biology, mechanism of action and translational strategy
Contribute to study planning, experimental timelines, and data-driven decision making for program advancement
Maintain accurate, well-organized experimental records while ensuring a safe, compliant, and reproducible lab environment
Identify opportunities to improve in vivo platforms and evaluate emerging technologies relevant to ImmunEdge’s pipeline
Qualification
Required
Bachelor's degree in biological science, with 8 years industry experience or Master's degree with 6 years industry experience in drug discovery or development, with significant hands-on experience in vivo models
Demonstrated experience designing, executing, and interpreting studies in murine syngeneic and transgenic disease models, particularly in oncology and/or immunology
Expertise in subcutaneous tumor implants and orthotopic surgeries is required
Proficient in dose administration via multiple routes, including intraperitoneal, intravenous, tail vein and oral gavage
Experience with blood collection (cheek bleed or RO), necropsy and sample processing in mice to support PK, PD, and biomarker analyses
Experience in flow cytometry (immune phenotyping, data analysis). Prior experience with Cytek spectral cytometry instruments is a plus
Experience in aseptic cell culture and perform cell line expansion for tumor implants in mice
Proficiency with standard laboratory techniques such as ELISA, MSD, qPCR, western blotting, and cytokine bead array is a plus
Demonstrated ability to independently analyze and interpret complex datasets using Flowjo, GraphPad Prism, generate publication-quality figures, and effectively communicate findings through slide presentations in departmental and cross-functional forums
Ability to independently plan and execute experiments, troubleshoot complex problems, and rigorously interpret scientific data
Strong collaboration, communication, technical writing, and organizational skills
Ability to thrive in a fast-paced, supportive start-up environment
Benefits
Comprehensive health (medical, dental, and vision) insurance for our employees and their families
A 401k plan
FSA plans (medical, dependent)
An Employee Assistance Plan
A holiday and paid time off plan
Company
ImmunEdge
ImmunEdge is a biopharmaceutical company committed to developing novel therapeutics for patients with serious or life-threatening diseases.
Redwood City, California, US
11-50 employeesH1B Sponsorship
ImmunEdge has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2023 (1)
Funding
Current Stage
Early StageCompany data provided by crunchbase