Novartis · 16 hours ago
Principal Scientist II
San Diego
Full-time
Onsite
Senior Level, Lead/Staff
$126K/yr - $234K/yr
5+ years expNovartis’ Neuroscience Genetics Medicine Unit is looking for a project leader focused on the discovery and development of innovative medicines for neurodegenerative disorders. The role involves leading a team in developing novel therapeutic strategies, collaborating with multidisciplinary teams, and communicating scientific strategies to stakeholders.
BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
Responsibilities
Contribute to creating and developing novel therapeutic strategies for neurodegenerative disease, with an emphasis on CNS drug delivery, oligonucleotide and/or AAV therapeutics
Communicate project strategy, scientific vision, and data to key stakeholders
Lead a team of associates in the design, execution, and analysis of experiments to deliver high quality data and enable timely project decisions
Deliver impact to projects by following both technical and conceptual trends in the neurodegenerative field
Develop and integrate models of neurodegenerative disease using in vivo systems in collaboration with multi-disciplinary teams across the organization
Collaborate with multidisciplinary teams, consisting of experts in molecular biology, drug discovery, biologics and chemistry
Expertly relay information to all levels of the organization, as well as with our external partners and collaborators
Qualification
Required
PhD in neuroscience, biology or a closely related field
5+ years (post PhD) of specific expertise in neurodegenerative diseases and/or CNS drug delivery, with two years in industry, highly preferred
2+ years' experience managing a team of associates
Deep understanding of the pathophysiology of neurodegenerative disease and/or CNS drug delivery
Demonstrated expertise in establishing in vivo models of neurodegenerative disease to study disease mechanisms
Exceptional proficiency in various laboratory methodologies within neuroscience, including gene expression, functional testing and imaging
Excellent problem-solving skills, diligent attention to detail, and the ability to work both independently and as a member of a complex matrix teams. Thinking creatively to tackle scientific and operational challenges in a fast-paced drug discovery environment
Preferred
Experience in animal models of neurodegenerative disease
Experience in CNS drug delivery modalities
Benefits
Health, life and disability benefits
A 401(k) with company contribution and match
A variety of other benefits
Generous time off package including vacation, personal days, holidays and other leaves
Company
Novartis
Novartis is a pharmaceutical company that researches and develops medicines for serious diseases to improve and extend people's lives.
10001+ employees
H1B Sponsorship
Novartis has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2024 (27)
2023 (23)
2022 (27)
2021 (31)
2020 (25)
Funding
Current Stage
Public CompanyTotal Funding
$2.49BKey Investors
Bill & Melinda Gates Foundation
2024-06-19Post Ipo Debt· $2.49B
2018-02-14Grant· $6.5M
2000-05-19IPO
Leadership Team
Daniel Grant
Vice President & Global Program Head
John von Brachel
VP, Head of Content Lab
Recent News
2026-01-23
2026-01-23
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