Principal Scientist II jobs in United States
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Novartis · 10 hours ago

Principal Scientist II

Novartis’ Neuroscience Genetics Medicine Unit is looking for a project leader focused on the discovery and development of innovative medicines for neurodegenerative disorders. The role involves leading a team in developing novel therapeutic strategies, collaborating with multidisciplinary teams, and communicating scientific strategies to stakeholders.

BiotechnologyHealth CareMedicalPharmaceuticalPrecision Medicine
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H1B Sponsor Likelynote

Responsibilities

Contribute to creating and developing novel therapeutic strategies for neurodegenerative disease, with an emphasis on CNS drug delivery, oligonucleotide and/or AAV therapeutics
Communicate project strategy, scientific vision, and data to key stakeholders
Lead a team of associates in the design, execution, and analysis of experiments to deliver high quality data and enable timely project decisions
Deliver impact to projects by following both technical and conceptual trends in the neurodegenerative field
Develop and integrate models of neurodegenerative disease using in vivo systems in collaboration with multi-disciplinary teams across the organization
Collaborate with multidisciplinary teams, consisting of experts in molecular biology, drug discovery, biologics and chemistry
Expertly relay information to all levels of the organization, as well as with our external partners and collaborators

Qualification

NeuroscienceCNS drug deliveryGene therapyVivo modelsLaboratory methodologiesData analysisTeam managementCollaborationCommunication skillsProblem-solvingAttention to detail

Required

PhD in neuroscience, biology or a closely related field
5+ years (post PhD) of specific expertise in neurodegenerative diseases and/or CNS drug delivery, with two years in industry, highly preferred
2+ years' experience managing a team of associates
Deep understanding of the pathophysiology of neurodegenerative disease and/or CNS drug delivery
Demonstrated expertise in establishing in vivo models of neurodegenerative disease to study disease mechanisms
Exceptional proficiency in various laboratory methodologies within neuroscience, including gene expression, functional testing and imaging
Excellent problem-solving skills, diligent attention to detail, and the ability to work both independently and as a member of a complex matrix teams. Thinking creatively to tackle scientific and operational challenges in a fast-paced drug discovery environment

Preferred

Experience in animal models of neurodegenerative disease
Experience in CNS drug delivery modalities

Benefits

Health, life and disability benefits
A 401(k) with company contribution and match
A variety of other benefits
Generous time off package including vacation, personal days, holidays and other leaves

Company

Novartis

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Novartis is a pharmaceutical company that researches and develops medicines for serious diseases to improve and extend people's lives.

H1B Sponsorship

Novartis has a track record of offering H1B sponsorships. Please note that this does not guarantee sponsorship for this specific role. Below presents additional info for your reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (14)
2024 (27)
2023 (23)
2022 (27)
2021 (31)
2020 (25)

Funding

Current Stage
Public Company
Total Funding
$2.49B
Key Investors
Bill & Melinda Gates Foundation
2024-06-19Post Ipo Debt· $2.49B
2018-02-14Grant· $6.5M
2000-05-19IPO

Leadership Team

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Daniel Grant
Vice President & Global Program Head
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John von Brachel
VP, Head of Content Lab
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Company data provided by crunchbase