Immunome, Inc. · 8 hours ago
Senior Research Scientist, ADME Bioanalytical
Bothell, Washington, United States
Full-time
Onsite
Mid, Senior Level
$107K/yr - $133K/yr
3+ years expImmunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. The Senior Research Scientist will play a key role in advancing Immunome’s preclinical programs by developing and executing bioanalytical assays and supporting method development for both small and large molecules in preclinical studies.
BiopharmaBiotechnologyMedicalPharmaceutical
Responsibilities
Perform sample extraction and preparation from a range of biological matrices for both large and small molecule analytes
Develop and optimize bioanalytical methods for ADCs and other modalities within preclinical settings
Maintain, operate, and troubleshoot chromatography and mass spectrometry instrumentation
Maintain a detailed and accurate electronic laboratory notebook in accordance with ALCOA+ principles
Evaluate bioanalytical data to support ADME studies and early research activities
Support pharmacokinetic, pharmacodynamic, and stability evaluations
Interpret and communicate bioanalytical results to the ADME group and cross-functional project teams
Prioritize responsibilities effectively in a dynamic environment with evolving timelines
Collaborate with cross-functional teams to align bioanalytical strategies with early research and translational objectives
Assist in managing outsourced bioanalytical studies, including preparation of method transfer packages and review of method validation and sample analysis reports for regulated preclinical studies
Qualification
Required
Bachelor's with a minimum of 5 years or Master's degree with a minimum of 3 years of experience in bioanalytical and/or analytical chemistry
Knowledge of regulatory guidance and industry best practice for LC-MS analysis of large and small molecules
Demonstrated expertise in LC-MS/MS for quantitative analysis from complex biological matrices using protein precipitation, solid-phase extraction, immunoprecipitation, or related techniques
Experience with quality and statistical evaluation of data using Sciex OS, Protein Metrics, Excel, GraphPad Prism, ChemDraw, and/or Skyline
Experience managing outsourced bioanalytical studies, including preparation of method transfer packages and review of method validation and sample analysis reports for regulated preclinical studies
Strong technical expertise in LC-MS/MS operation, troubleshooting, and method development
Solid understanding of ADME principles, pharmacokinetics, pharmacodynamics, and bioanalytical workflows
Ability to independently analyze, interpret, and present scientific data
Strong organizational skills with the ability to manage competing priorities
Effective written and verbal communication skills supporting cross-functional collaboration
Commitment to data integrity and high-quality documentation
Company
Immunome, Inc.
Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted therapies designed to improve outcomes for cancer patients.
51-200 employees
H1B Sponsorship
Immunome, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (1)
Funding
Current Stage
Public CompanyTotal Funding
$998.85MKey Investors
JPEO-CBRNDU.S. Department of DefenseRobin Hood Ventures
2025-12-16Post Ipo Equity· $400M
2025-01-29Post Ipo Equity· $150M
2024-02-13Post Ipo Equity· $230M
Leadership Team
Clay Siegall
President and CEO
Purnanand D. Sarma
President & CEO
Recent News
2026-01-09
BioWorld Financial Watch
2025-12-19
Company data provided by crunchbase