Bexorg, Inc. · 18 hours ago
Research Scientist, Human Brain Tissue Specialist
New Haven, CT
Full-time
Onsite
Mid, Senior Level
3+ years expBexorg, Inc. is dedicated to advancing medicine through novel technologies and solutions aimed at improving human life. They are seeking a Research Scientist to lead the acquisition and assessment of postmortem human brain tissue, focusing on neurodegenerative diseases. The role involves hands-on expertise in tissue processing, collaboration with clinical teams, and ensuring compliance with ethical guidelines.
Artificial Intelligence (AI)Big DataBiotechnology
Responsibilities
Lead precise dissection of postmortem human brain tissue in coordination with neurosurgeons
Ensure rigorous documentation, labeling, and inventory control for all biospecimens
Follow and enhance SOPs to maintain sample integrity from acquisition through analysis
Support targeted tissue sampling aligned with project-specific neuropathological goals
Prepare tissue and biofluid samples for downstream histological, immunohistochemical, and molecular workflows
Partner with clinical and research teams to identify and process regions of interest across major neurodegenerative disease phenotypes
Maintain detailed dissection notes, donor metadata, and clinical history in structured digital systems
Ensure full compliance with ethical guidelines and institutional protocols for human tissue research
Continuously improve protocols for tissue preservation, staining, and analysis
Mentor junior lab members and provide hands-on training in dissection techniques
Collaborate across pathology, molecular biology, and informatics teams to drive integrated project execution
Contribute to team meetings with clear updates on sample availability, processing timelines, and emerging challenges
Qualification
Required
Lead precise dissection of postmortem human brain tissue in coordination with neurosurgeons
Ensure rigorous documentation, labeling, and inventory control for all biospecimens
Follow and enhance SOPs to maintain sample integrity from acquisition through analysis
Support targeted tissue sampling aligned with project-specific neuropathological goals
Prepare tissue and biofluid samples for downstream histological, immunohistochemical, and molecular workflows
Partner with clinical and research teams to identify and process regions of interest across major neurodegenerative disease phenotypes
Maintain detailed dissection notes, donor metadata, and clinical history in structured digital systems
Ensure full compliance with ethical guidelines and institutional protocols for human tissue research
Continuously improve protocols for tissue preservation, staining, and analysis
Mentor junior lab members and provide hands-on training in dissection techniques
Collaborate across pathology, molecular biology, and informatics teams to drive integrated project execution
Contribute to team meetings with clear updates on sample availability, processing timelines, and emerging challenges
Preferred
Advanced degree (PhD, MD, or Master's) in Neuropathology, Neurology, Anatomy, or related field
3–5+ years of direct experience in human brain tissue dissection, preferably in a clinical or research pathology environment
Deep working knowledge of cortical and subcortical brain anatomy
Proven track record of handling postmortem human brain tissue under time-sensitive conditions
Flexibility to support evening/weekend work for acute tissue processing
Strong written and verbal communication skills, with the ability to clearly present complex biological concepts to non-specialists
Experience partnering with brain banks or academic neuropathology programs
Familiarity with neurodegenerative disease staging (e.g., Braak, CERAD) and hallmark lesion identification
Proficiency in frozen sectioning, microdissection, or digital pathology workflows
Exposure to image analysis tools for neuropathological quantification
Demonstrated intellectual curiosity and a track record of solving novel, cross-disciplinary problems
Ability to thrive in fast-paced, evolving research environments with minimal supervision
Experience contributing to a high-impact, mission-driven research culture; startup or fast-growth lab experience a plus
Comfortable navigating ambiguity and building systems or processes from scratch when needed
Company
Bexorg, Inc.
Bexorg is a privately held techbio company with the first-ever full tech stack platform to support CNS drug discovery and development in the human brain in a way that has not been possible before.
11-50 employees
H1B Sponsorship
Bexorg, Inc. has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (2)
2023 (1)
Funding
Current Stage
Early StageTotal Funding
$23MKey Investors
Engine Ventures
2025-10-15Series A· $23M
Leadership Team
Zvonimir Vrselja
Chief Executive Officer
Sean Murphy
Chief Technology Officer
Recent News
2025-11-19
2025-11-16
Company data provided by crunchbase