Amgen · 6 hours ago
Senior Scientist - Immunology/Immunogenicity
US - California - Thousand Oaks
Full-time
Onsite
Mid, Senior Level
$142K/yr - $160K/yr
4+ years expAmgen is a biotechnology company dedicated to serving patients living with serious illnesses. They are seeking a Senior Scientist to perform in vitro assays to assess the immunogenic risk of their protein therapeutic pipeline, collaborating with various teams to drive project execution and mentor junior staff.
BiotechnologyHealth CareManufacturingPharmaceutical
Responsibilities
Perform various cell-based assays using primary human cells, such as dendritic cell or B cell co-culture with T cells using T cell proliferation, cell surface expression, and cytokine production as a readout
Development novel in vitro assays to assess immunogenic risk
Collaborate with colleagues to execute MHC-associated peptide proteomics (MAPPs) experiments to identify potential T cell epitopes within protein therapeutic candidates
Design and/or modify assays based on the mechanism of action of the drug candidate
Implement the cell-based assays using an automated, high throughput platform
Generate data, interpret, and summarize results for presentation at internal meetings as needed
Summarize results into study reports for incorporation into regulatory documents
Mentor a lab-based scientific team, driving project execution while supporting individual growth and long-term career development
Qualification
Required
Doctorate Degree
Master's degree and 2 years in Immunology or related experience
Bachelor's degree and 4 years in Immunology or related experience
Preferred
Expertise in RNA biology with a record of accomplishments including impactful first author peer-reviewed publications
Extensive research experience, including postdoctoral training, in biophysics, biochemistry, molecular and cellular biology, or related disciplines
Broad knowledge of assay development and NGS technologies
Strong reasoning, data analysis, attention to detail, and problem-solving skills
Excellent communication, interpersonal, and organizational skills
Desire to be a team player in a dynamic, cross-functional environment
Benefits
Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
Stock-based long-term incentives
Award-winning time-off plans and bi-annual company-wide shutdowns
Flexible work models, including remote work arrangements, where possible
Company
Amgen
Amgen is a biotechnology company that develops and manufactures human therapeutics for various illnesses and diseases.
10001+ employees
H1B Sponsorship
Amgen has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (429)
2024 (485)
2023 (485)
2022 (540)
2021 (460)
2020 (444)
Funding
Current Stage
Public CompanyTotal Funding
$28.5B2022-12-12Post Ipo Debt· $28.5B
1983-06-17IPO
Leadership Team
Robert Bradway
Chairman and Chief Executive Officer
Jay Bradner
Executive Vice President of R&D, and Chief Scientific Officer
Recent News
2026-01-24
2026-01-22
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