Insmed Incorporated · 9 hours ago
Scientist II, Gene Therapy
San Diego, CA
Full-time
Onsite
Mid, Senior Level
$80K/yr - $102K/yrInsmed Incorporated is a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases. They are seeking a Scientist II on the Gene Therapy Research team to lead critical gene replacement therapy projects and develop specialized in vitro assays to confirm protein function.
BiotechnologyMedicalPharmaceutical
Responsibilities
Lead highly independent and critical projects aimed at the functional assessment of therapeutic candidates, specifically regarding gene replacement therapies for conditions such as Stargardt Disease
Spearhead the development of critical in-vitro assays to demonstrate therapeutic efficacy, such as confirming enzymatic or structural function
Supervise, manage, and train junior scientific staff (e.g., Senior Research Associates) to support laboratory operations and experimental execution
Analyze complex experimental data and oversee advanced histology workflows, including immunohistochemistry (IHC), RNA in situ hybridization (RNA and Base scope), and quantitative microscopy
Prepare scientific reports and author manuscripts for peer-reviewed journals
Present research findings to cross-functional internal teams and external stakeholders (such as at scientific conferences) to facilitate project progress and support regulatory submissions
Specialized expertise in designing and executing complex in vitro assays for assessing the functional activity of gene therapy products
Proficiency in conducting in vivo studies, including mouse handling, surgeries, and tissue collection for efficacy and functional analysis
Competence in implementing and optimizing histology workflows, specifically IHC and RNA in situ hybridization, as well as performing quantitative/qualitative analysis of histological samples
Expertise molecular biology, mechanisms, and evaluating the yield, potency, and functionality of gene therapy systems
Ability to manage project-level budgets and oversee the allocation of laboratory resources
Qualification
Required
Ph.D in Molecular Biology or related field
Relevant post-doctoral or industrial experience
Proven ability to work independently on critical path projects
Strong leadership skills for supervising and training support staff
Excellent communication skills for presenting data internally and externally
Lead highly independent and critical projects aimed at the functional assessment of therapeutic candidates, specifically regarding gene replacement therapies for conditions such as Stargardt Disease
Spearhead the development of critical in-vitro assays to demonstrate therapeutic efficacy, such as confirming enzymatic or structural function
Supervise, manage, and train junior scientific staff (e.g., Senior Research Associates) to support laboratory operations and experimental execution
Manage project-specific expenditures and allocate resources effectively to ensure funds are used to advance the program
Analyze complex experimental data and oversee advanced histology workflows, including immunohistochemistry (IHC), RNA in situ hybridization (RNA and Base scope), and quantitative microscopy
Prepare scientific reports and author manuscripts for peer-reviewed journals
Present research findings to cross-functional internal teams and external stakeholders (such as at scientific conferences) to facilitate project progress and support regulatory submissions
Specialized expertise in designing and executing complex in vitro assays for assessing the functional activity of gene therapy products
Proficiency in conducting in vivo studies, including mouse handling, surgeries, and tissue collection for efficacy and functional analysis
Competence in implementing and optimizing histology workflows, specifically IHC and RNA in situ hybridization, as well as performing quantitative/qualitative analysis of histological samples
Expertise in molecular biology, mechanisms, and evaluating the yield, potency, and functionality of gene therapy systems
Ability to manage project-level budgets and oversee the allocation of laboratory resources
Benefits
Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP)
Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration
401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock Purchase Plan (ESPP), and company-paid life and disability insurance
Company Learning Institute providing access to LinkedIn Learning, skill building workshops, leadership programs, mentorship connections, and networking opportunities
Employee resource groups, service and recognition programs, and meaningful opportunities to connect, volunteer, and give back
Company
Insmed Incorporated
Insmed is a people-first global biopharmaceutical company striving to deliver first- and best-in-class therapies to transform the lives of patients facing serious diseases.
Founded in 1988
1001-5000 employees
H1B Sponsorship
Insmed Incorporated has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Represents job field similar to this job
Trends of Total Sponsorships
2025 (20)
2024 (6)
2023 (14)
2022 (8)
2021 (1)
2020 (5)
Funding
Current Stage
Public CompanyTotal Funding
$4.56BKey Investors
CureDuchenne Ventures
2025-06-11Post Ipo Equity· $750M
2024-05-30Post Ipo Equity· $650M
2023-05-08Post Ipo Equity· $0.5M
Leadership Team
Will Lewis
Chairman and Chief Executive officer
Walter R. Perkins
Chief Technology Officer
Recent News
2026-01-13
Company data provided by crunchbase